By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection. See our privacy policy for more information on the use of your perso...
Cells with H3K27me3-rich regions knockout also show changes in phenotype associated with cell identity, and altered xenograft tumor growth. Finally, we observe that H3K27me3-rich regions-associated genes and long-range chromatin interactions are susceptible to H3K27me3 depletion. Our results ...
Recently, nanometer sized vesicles (termed exosomes) have been described as a component of urine. Such vesicles may be a useful non-invasive source of markers in renal disease. Their utility as a source of markers in urological cancer remains unstudied.
aSimulations of translation elongation and ejection of nascent Luciferase were performed with a coarse-grain ribosome representation (ribosomal proteins and RNA are displayed in red and gray, respectively). Domains 1, 2, 3, and 4 of Luciferase are displayed in silver, light green, magenta, and l...
Due to a lack of research on the critical non-coding RNAs in regulating ferroptosis, our study aimed to uncover the crucial ones involved in the process. We found that LINC01133 could make pancreatic cancer cells more resistant to ferroptosis. A higher e
Some misfolded protein conformations can bypass proteostasis machinery and remain soluble in vivo. This is an unexpected observation, as cellular quality control mechanisms should remove misfolded proteins. Three questions, then, are: how do long-lived,
We also share information about your use of our site with our social media, advertising and analytics partners who may combine it with other information that you’ve provided to them or that they’ve collected from your use of their services. Show details Deny Allow all...
NT. NPC; may be involved in nuclear transport, particularly of RNA. Nucleus; component of the RNA polymerase II transcription machinery Nucleus/cytoplasm; dual-specificity transcription factor regulating the expression of both MAX-network and T-box family target genes NPC; thought to play roles ...