Subcutaneous 4T1 tumour model was established by injection of 1064T1 cells in 100 µL PBS into the right flank of female BALB/c mice. After 1 week, all drugs were administered to mice by intravenous (i.v.) injection 12 hours before neutron irradiation. ...
BCI cells are cultured on Primaria plates (BD Biosciences, San Jose, CA, USA) as previously described.23,45 Serial dilution in vivo (BPLER/HMLER) Single-cell suspensions were prepared in a WIT:Matrigel (1:1) mixture and injected in 25 μl (orthotopic) or 100 μl (subcutaneous) volumes...
Gene duplication is a normal evolutionary process. If there is no selective advantage in keeping the duplicated gene, it is usually reduced to a pseudogene and disappears from the genome. However, some paralogs are retained. These gene products are likel