4b). However, such strategies always yield the desired rotaxane as an ammonium salt with the crown ether interacting, through multiple hydrogen bonds, with the protonated nitrogen on the axle. Fig. 4: Hydrogen bonds in the synthesis of a rotaxane. Two synthetic strategies involving hydrogen bond...
Aniline vinylether CAN cat syn cis-2-methyl-4-hydroxy sun tetrahydroquinoline tetrahydroquinolinol Pd/C O2 dehydrogenate oxidat quinolineMenendez, J C
Moreover, Lys802 made a hydrogen bond interaction with one fluorine atom of the trifluoromethyl of Alpelisib. Amide group and residue of Gln859 and Val851 performed a pair of donor–acceptor hydrogen bonds. Compound 8 showed H-bonding with essential Val851 residue and chlorine atom make a H-...
Because there are hydrogen bonds between the molecules of microcrystalline cellulose, the hydrogen bonds are associated when pressed, so it has a high degree of compressibility and is often used as a binder; when the compressed tablet encounters liquid, water quickly ...
Molecular docking studies suggested that the sulfonylamidine side chain could form direct hydrogen bonds with Topo I, providing insights into the molecular interactions responsible for their cytotoxic activity. In addition to hydrogen bonding, the hydrophobic interactions with Topo I and π-π stacking ...
2,3-BDO can be produced by catalytic hydrogenation of saccharides with hydrogen at elevated pressures and temperatures, Fig.2. Hirth et al. [223] reported that by increasing temperature to approximately 225 °C or higher, selectivity can be shifted toward C2, C3, C4, and/or C6 polyols, suc...
energies contained in the bonds for example the hydrogen bonds, and therefore breaks these bonds and releases the droplets of the three-dimensional network. These temperatures are dependent on the composition of the gel and more particularly on the size of the droplets and the length of the poly...
In addition, a hydrogen bond occurs between the O6 atom of the coordinating guanine and the proximal amine group of the ethylenediamine ligand. The carrier ligands of RAED-C in the guanine adducts appear to form favourable interactions with the double helix, but the conformation of the DNA ...
(67.6 g ; 0.20 mole) in anhydrous ether (200 ml) kept below -40' under a nitrogen atmospllere, an ethereal solution of methyllithi~~m(50 ml; 0.20 mole) Ivai added, with stirring, during 3 h. 'Then the mixture was stirred a t room t e ~ n p e r a t ~ ~forre a n ...
N-acylated 11-amino derivatives of papulacandin A or B of the formula I ##STR1## in which Pap is the remainder of papulacandin A or B, R represents methyl or hydrogen and Ac represents the acyl radica