These results are very exciting on several fronts. First, this phytoestrogen has been shown to provide a significant anti-osteoporotic benefit. Second, if a dose of estradiol were extrapolated to provide a comparable amount of bone protection in women as 8-PN provided in these rats, it would a...
[68]. A very early study onn= 8 relapsing MS women reported a relationship of progesterone to estradiol ratio during the luteal phase on the number and volume of contrast brain lesions. In one analysis, MS patients vs. controls reported more irregular cycles, and more premenstrual symptoms [...