The accuracy of MiXcan and PrediXcan GReX prediction models trained using GTEx v8 data for 125 mammary tissue samples from EA women was initially evaluated in an independent dataset of 103 tumor-adjacent normal mammary tissue samples from EA women in The Cancer Genome Atlas (TCGA). MiXcan estima...
“Pancreatic cancer is very aggressive, and patients who present with the cancer at an early stage are a minority,” says Dr. George Yacoub, medical oncologist and Earl’s primary oncologist at Wake Forest Baptist. “Those with early stage pancreatic cancer can undergo surgery to remove the tu...
The spermatogonic cells contained only primary spermatocytes with shrunk oval nuclei. Moreover, both spermatids and spermatozoa were absent and the lumen of the seminiferous tubules contained a lot of 84 Egypt. J. Exp. Biol. (Zool.), 2: 81 – 91 (2006) large pleomorphic vacuoles filled ...
Using a lineage-tracing approach, we show that adult rodent prostate basal and luminal cells are independently self-sustained in vivo. Disrupting the tumor suppressor Pten in either lineage led to prostate cancer initiation. However, the cellular composition and onset dynamics of the resulting tumors...
Anatomic changes can be pronounced during treatment. In this example, planning CT scan and CTV contours are shown on the left. On the right, a mid-course CT (three weeks into treatment) demonstrates significant reduction in gross tumor (thick red line). Baseline CTVs have been overlaid via ...
only specific parts can move around the axis. Most existing nanomachines have been designed so that the mobile components and axis of the large structure are present on the same layer. Thus, these components undergo simultaneous movement, which complicates the desired control of a specific part. ...
Second, Cape Town's water system neared disaster in part because demand management seemed to have reached its limits. Starting late last year, the city imposed a limit on water consumption of 87 litres per person per day. That ceiling thereafter shrunk to50 litres per person per day. ...
Tumor budding (TB) histology has become a critical biomarker for several solid cancers. Despite the accumulating evidence for the association of TB histology with poor prognosis, the biological characteristics of TB are little known about in the context related to the tumor immune microenvironment (TI...
I lost an ovary and fallopian tube due to a ruptured ectopic pregnancy when I was 21. I had my first child at 38 after one single act of unprotected sex. I had my second child at 40 after 1 single act of unprotected sex. My husband and I have scary fertility levels. He got a vas...