The role of cAMP and its downstream targets in neurite growth in the adult nervous system. Nuerosci. Lett. 2017. 653 56-63.Batty NJ, Fenrich KK, Fouad K. 2017. The role of cAMP and its downstream targets in neurite growth in the adult nervous system. Neurosci Lett 652:56-63....
ABCA1 is a 240 kDa protein belonging to a large family of conserved transmembrane proteins that transport a wide variety of substrates, including ions, drugs, peptides, and lipid across cell membranes (5). ABC transporters have been associated with many diseases such as drug-resistant cancer (...
Fig. 1 The cAMP signaling pathways. The extracellular cAMP can be converted into AMP by plasma membrane-anchored ecto-PDE, followed by the conversion of AMP into adenosine by CD73. Ligands-engaged Gs- or Gi-coupled receptors may stimulate or inhibit cAMP synthesis, respectively. The ABCC transp...
Sessions started with the delivery of one food pellet (45-mg, Bio-Serv, Frenchtown, NJ) and the first trial commenced on pellet retrieval. A nose poke into the magazine initiated a 5-s intertrial interval (ITI) and illuminated the 2-W house light. At the end of the ITI, a 1.0-s ...
Phosphodiesterase (PDE)4 inhibitors: anti-inflammatory drugs of the future? Trends Pharmacol Sci. 1997;18:164–71. Article CAS PubMed Google Scholar Kamenetsky M, Middelhaufe S, Bank EM, Levin LR, Buck J, Steegborn C. Molecular details of cAMP generation in mammalian cells: a tale of ...
Several drugs useful in treatment of cardiovascu- lar diseases, such as HMG-CoA reductase inhibitors[8] and metformin[9], have been proved to possess anti-inflammatory effects. In the present study, we investigate the possible anti-inflam- matory effect of rimonabant in endothelial cells with ...
Faculty Opinions recommendation of Prostaglandin E2 promotes human CD34+ cells homing through EP2 and EP4 invitro. H Broxmeyer - Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature 被引量: 0发表: 2019年 Differential Effect of Antiallergic Drugs on IgE-Mediated Cutaneous ...
Exchange proteins directly activated by cyclic AMP (Epac) were discovered 10 years ago as new sensors for the second messenger cyclic AMP (cAMP).
The cells were analyzed using a FACSCalibur system (BD Biosciences, Franklin Lakes, NJ), and the results were processed using CellQuest software (BD Biosciences). The number of cells in the lung was determined by multiplying total lung cells by the percentage of CD4+ or CD8+ T-cells. To ...
Audio: The War On Drugs Take On Bob Dylan’s ‘Tangled Up In Blue’ October 7, 2014 Music Critics To Read at LitQuake Event – Gina Arnold, Joel Selvin, Michael Goldberg & More October 7, 2014 Remembering Bob Dylan from the Days of ’64 –‘it was worth the two-year marriage ...