Furthermore, these effects of rolipram could be reversed by the SIRT1 inhibitor sirtinol. In conclusion, rolipram can play a neuroprotective role in the pathological process of ICH by activating the cAMP/AMPK/SIRT1 pathway.doi:10.1038/s41598-021-98743-wXiao-Liu Dong...
The protective effect of the PDE-4 inhibitor rolipram on intracerebral haemorrhage is associated with the cAMP/AMPK/SIRT1 pathway.doi:10.1038/S41598-021-98743-WXiao-Liu DongYan-Hui WangJing XuNan ZhangNature Publishing Group