三组肿瘤组织中TTF-1、NapsinA、P40、CK5/6均表达阳性,S100A6实验组、空载体组、空白对照组肿瘤组织中P63表达阳性率分别为7/7、3/4、3/4。 结论S100A6可抑制人肺癌细胞株Calu-6增殖,对人肺癌细胞株Calu-6向肺腺癌或肺鳞癌分化方向未见影响。 关键词: 肺肿瘤;肺腺癌;癌,鳞状细胞;S100A6;Calu-6;生物标记...
存储条件:粉末 -20°C 3 年 4°C 2 年 溶剂中 -80°C 1 年 -20°C 6 个月 运输条件:美国大陆的室温;其他地方可能有所不同。 产品活性:Niraparib (MK-4827) 是高效的,具有生物口服利用度的 PARP1 和 PARP2 抑制剂,IC50 分别为 3.8 nM 和 2.1 nM。Niraparib 抑制 DNA 损伤修复,诱导凋亡 (apo...
ʃ4．34)%．Conclusion:Sinomenine significantly inhibited the proliferation and promoted the apoptosis of lung canc-er cells．【Key words】Sinomenine;lung cancer;apoptosis Modern Oncology2013，21(02):0267－0270 【摘要】目的：探讨青藤碱对肺癌细胞株Calu－1增殖、凋亡影响及相关作用机制。方法：青藤碱150...
表达宿主: Human Cells CALU / Calumenin Protein QC Testing 纯度: > 90% as determined by SDS-PAGE SDS-PAGE 内**: < 1.0 EU per μg of the protein as determined by the LAL method 稳定性: Samples are stable for up to twelve months from date of receipt at -70℃ ...
The inhibition of proteasome function has emerged as a useful strategy to maneuver apoptosis. In the present study, we evaluated the effects of MG132 as a proteasome inhibitor on the growth of Calu-6 lung cancer cells in relation to the cell cycle, cell death, reactive oxygen species (ROS)...
We recently established that 20 μM FCCP induced apoptosis in Calu-6 cells via the activation of caspase-8, caspase-9 and caspase-3, and all of the caspase inhibitors attenuated the intracellular O2− levels in FCCP-treated Calu-6 cells (unpublished data). In the present study, we investi...
The inhibition of proteasome function has emerged as a useful strategy to maneuver apoptosis. In the present study, we evaluated the effects of MG132 as a proteasome inhibitor on the growth of Calu-6 lung cancer cells in relation to the cell cycle, cell death, reactive oxygen species (ROS)...
学术范收录的Journal MG132, a proteasome inhibitor decreased the growth of Calu-6 lung cancer cells via apoptosis and GSH depletion.,目前已有全文资源,进入学术范阅读全文,查看参考文献与引证文献,参与文献内容讨论。学术范是一个在线学术交流社区,收录论文、
Calu-6/S100A6 cellsshowed a weakening trend in the cell behaviours of proliferation, migration and inva-siveness, while had an enhancement of cell apoptosis, with all P < .05. The cell cycle ofCalu-6/S100A6 cells had a reduction of S phase and an increase of G1 phase (P < ...
Cells,CECs)因与肿瘤血管生成 及肿瘤性血管内皮细胞凋亡、肿瘤病理类型及分化、生长、播散转移均可能有密 切关系‘1矗",而成为当今国际上研究的热点。 本实验旨在通过检钡gEndostatin干预后肿瘤组织及外周血中与血管生成、凋 第9页共52页 硕士研究生学位论文 亡、增殖等生物行为相关的指标表达、初步探讨Endostatin的...