ConclusionS100A6 can inhibit the proliferation of human lung cancer cell line Calu-6, but has no effect on the differentiation of human lung cancer cell line Calu-6 into lung adenocarcinoma or lung squamous cell carcinoma. KEYWORDS: Lung neoplasms;Adenocarcinoma of lung;Carcinoma, squamous cell;S10...
【Abstract】Objective:To evaluate the effect of Sinomenine on the proliferation，apoptosis in lung cancer cell lines Calu－1and related mechanism．Methods:After deal with different dose of Sinomenine150μg/ml，200μg/ml，250μg/ml and control group(0μg/ml)in12h，24h，36h later，to use MTT...
Vorum H. et al., 1999, Exp Cell Res. 248 (2): 473-81. 规格:50ug 关键词:CALU / Calumenin Protein,价格,参数,实验室耗材,生化试剂,上海创赛,博飞美科,实验仪器,厂家 CANSPEC品质提供的CALU / Calumenin Protein|价格|参数性能**,其优良的品质满足您不同实验的多种需求。
In contrast, BSO, a well-known inhibitor of GSH synthesis, aggravated GSH depletion, oxidative stress of O2− and cell death in FCCP-treated cells. Taken together, our data suggested that FCCP as an O2− generator, induces apoptosis via the depletion of intracellular GSH contents in Calu-...
cell behaviours of proliferation, migration and inva-siveness, while had an enhancement of cell apoptosis, with all P < .05. The cell cycle ofCalu-6/S100A6 cells had a reduction of S phase and an increase of G1 phase (P < .05).In animal study, after 5 weeks of cell ...
cell lungcancer,NSCLC)占其中的80% 左右,临床确诊时50%的患者已发生远处转移,且相当一部分是常规检查难以 发现的,造成术后很快复发。目前,治疗远方转移的主要方法为化疗,但治疗效 果差,容易发生耐药。因而靶向治疗成为当今研究的热点,这之中以内皮抑素较 为理想,许多国内、外学者尝试将其用于临床治疗。但对其作用...
apoptosiscoloncancerPatch clamp methods and reverse transcription-polymerase chain reaction (RT-PCR) were used to characterize an apical K+ channel in Calu-3 cells, a widely used model of human airway gland serous cells. In cell-attached and excised apical membrane patches, we found an inwardly...
PX-12 induced the growth inhibition of Calu-6 cells with IC50 of nearly 3 渭M at 72 h. In contrast, PX-12 did not affect the growth of human small airway epithelial cells (HSAECs). Cell cycle distribution analysis indicated that PX-12 significantly induced a G2/M phase arrest in Calu...
apoptosismitochondriaCalu-6Arsenic trioxide (ATO) can regulate many biological functions such as apoptosis and differentiation in various cells. We investigated an involvement of ROS such as H2O2 and O, and GSH in ATO-treated Calu-6 cell death. The levels of intracellular H2O2 were decreased in ...
ApoptosisCell ProliferationGene Expression Regulation, NeoplasticLoss of expression and p53 mutations are critical events in the early stages of lung carcinogenesis.The restoration of Fhit function in -negative cancer cells has been reported to cause tumour suppression by inhibition of cell proliferation ...