Comparing the Cockcroft-Gault and MDRD equations for calculation of GFR and drug doses in the elderly. Nat Clin Practice 2007;3:644-5.Berman N, Hostetter TH (2007) Comparing the Cockcroft Gault and MDRD equations for calculation of GFR and drug doses in the elderly. Nat Clin Pract ...
Glomerular filtration rate is an expression of the quantity of glomerular filtrate formed each minute in the nephrons of both kidneys, usually measured by the rate of clearance of creatinine. Glomerular filtration rate (GFR) is a test used to check the functioning levels of the kidneys. ...
Elderly individuals are at increased risk for toxicity: Impaired renal function Decreased muscle mass May have comorbidities Dose-response curve: A dose-response curve is a useful graphic that allows for a visual comparison of the dose needed for efficacy against harm. Image by Lecturio....
Since these formulas may not perform equally in different sub- jects, the comparison made between the formulas depends on the subjects under study.12 The current study was designed to compare the prognostic abilities of different calculation formulas for the GFR in elderly Chinese patients with CAD...
ElderlyEstimated GFRSerum creatinineSerum Cystatin CEquationAt present, estimated glomerular filtration rate (eGFR) remains the most frequently utilized parameter in the evaluation of kidney injury severity. Numerous equations have been formulated based on serum creatinine (Scr) or serum cystatin C (Cysc...