Equilibrium dialysis showed that four Ca2+ ions bind to one delta-crystallin tetramer with an affinity of 4.3 x 10(3) M-1. Analysis of the amino acid sequence of delta-crystallin reveals the presence of a calmo
The two calcium sites of parvalbumin were found to be strongly cooperative in binding Ca 2+ ion. Up to four calcium ions were found to bind to calmodulin at high calcium concentration levels. Strong cooperativity was detected between the third and fourth Ca 2+ binding sites of calmodulin (...
where ICa and IM are the currents due to calcium ions and due to all monovalent ions, respectively; \({[{{{\rm{Ca}}}^{2+}]}_{{{\rm{o}}}\) is the extracellular calcium concentration; [M] is the concentration of monovalent ions, assumed to be identical inside and outside the cel...
Ionic structure of phospholipid membranes, and binding of calcium ionsIonic structure of phospholipid membranes, and binding of calcium ionsdoi:10.1016/0005-2736(73)90073-4Radiotracer measurements of adsorption showed that the binding of Ca2+ with the phosphate groups of phosphatidylserine, phosphatidylet...
study25. The high N of PAA grafted chains made the two adjacent PAA grafted chains bind to calcium ions more efficient due to the closer spatial distance, causing Ca-CMC-g-PAA complex more stable and the inhibition effect enhanced25,53. Furthermore, high N of PAA grafted chains meant more...
Calcium alginate is incompatible with alkalis and alkali salts. Propranolol hydrochloride has been shown to bind to alginate molecules, suggesting that propranolol and calcium ions share common binding sites in the alginate chains; the formation of the calcium alginate gel structure was impeded in the...
In 1883, Ringer showed that to get isolated hearts to contract, it was necessary to have Ca2+ ions in the perfusion medium [421]. This was the first demonstration of the critical role of calcium in cellular activity. Remarkably, a hundred years passed before the importance of calcium was re...
(G) residues, which are responsible for its ability to form gel in the presence of calcium ions. This property is central to its functionality, as the divalent calcium ions create junction zones between the G-blocks, leading to the formation of a three-dimensional network. Additionally, ...
Complexation of metal ions, especially of polyvalent metal ions, by a spirobenzopyran dimer bridged by a diaza-18-crown-6 moiety at the 8-position induced remarkable isomerization of its spiropyran moiety to the corresponding merocyanine even under dark conditions. Crowned bis(spirobenzopyran) can ...
(Gulmann et al., 2002; Nonaka et al., 2008). Through its ability to bind Ca2+ions,phospholipids,inositol polyphosphatesor other proteins, the protein kinase C mediates a wide range of intracellular processes, e.g. the PI3K/IP3/PKC signalling pathway, secretion, cell growth and differentiation...