utilize for receptor binding, influx through channels, flux through transporters or pumps or for intracellular second messenger signaling is calcium in the nervous system.Ca 2+ and Ca 2+ Signaling The calcium ion (Ca 2+ ) is a ubiquitous ion and second messenger found in all living organisms....
Calcium-activated non-selective channels in the nervous system In the decade, since the first description of calcium-activated non-selective (CAN) channels in cardiac myocytes, pancreatic acini and neuroblastoma, this ... LD Partridge,TH Müller,D Swandulla - 《Brain Research Reviews》...
the receptor has also been investigated in cells and tissues not directly involved in calcium homeostasis, e.g., the nervous system (NS), where it plays crucial roles in early neural development for the differentiation of neurons and glial cells, as well as in the adult nervous system for sy...
Nuclear calcium is an important mediator of activity-dependent gene expression in the nervous system. It serves as a signalling end point in synapse-to-nucleus communication and activates gene programmes needed for the long-term implementation of many neuroadaptations, including memory consolidation, acq...
In 1883, Ringer showed that to get isolated hearts to contract, it was necessary to have Ca2+ ions in the perfusion medium [421]. This was the first demonstration of the critical role of calcium in cellular activity. Remarkably, a hundred years passed before the importance of calcium was re...
(B) Details of the dissection process, in which the MB is exposed for imaging. (C) Left: odor delivery system which simultaneously allows image acquisition and odor delivery to the fly. Middle: 3D volume rendering of a 3D stack after acquisition. Right: maximum intensity projections of nuclei...
Spedding M, Kilpatrick AT, Alps BJ: Activators and inactivators of calcium channels: effect in the central nervous system. Fundam Clin Pharmacol3: 3-29, 1989Speddings M, Kilpatrick AT, Alps BJ (1989) Activators and inactivators of calcium channels: effects in the central nervous system. ...
The chapter deals with voltage-gated calcium channel antagonists for the central nervous system. Voltage-gated calcium channels are Ca2+ selective pores in the plasma membrane of conductive cells. Voltage-gated calcium channels represent a critical step in nerve impulse initiation and transmission and ...
Method for pain therapy and/or for influencing the vegetative nervous system In an apparatus and a method for pain therapy and/or for influencing the autonomic nervous system, at least one pulse-like wave is conducted onto a neurally sensitive region with an apparatus, namely a source of pulse...
Calcium imaging with protein-based indicators1,2 is widely used to follow neural activity in intact nervous systems, but current protein sensors report neural activity at timescales much slower than electrical signalling and are limited by trade-offs bet