2. Most importantly, calcium homeostasis is regulated by the hormones PTH and active vitamin D (1,25(OH)2Vit D) on the kidney, gut and bone tissue [3] establishing a delicate and balanced flux of free calcium of major physiological importance [4,5]. Increased calcium levels, defined as ...
which results in adverse effects on bone health.2,31,25-Dihydroxyvitamin D3[1,25(OH)2D3], the hormonally active form of vitamin D, is the major controlling hormone of intestinal calcium absorption.4Calcium homeostasis is also regulated by parathyroid hormone and ionized calcium.1,5This review...
As cytosolic and organellar calcium homeostasis is regulated by calcium channels, the illustration of correlations between calcium channels and autophagy activities under various situations will help discover the calcium-dependent mechanisms of autophagy regulation. The consequence of calcium accumulation in ...
Calcium homeostasis in human melanocytes : role of transient receptor potential melastatin 1 ( TRPM1 ) and its regulation by ultraviolet light Calcium homeostasis in human melanocytes : role of transient receptor potential melastatin 1 ( TRPM1 ) and its r ...
Urinarycalcium homeostasisis regulated by thegastrointestinal tract, the kidneys, and bone and by the hormonesparathyroid hormone(PTH) andcalcitriol. Approximately 99% of the calcium in the body is contained within the bone mineral. Dailybone resorptionand bone formation, which in healthy, nonpregnant...
Thus, calcium is critically involved in synaptic activity and memory formation by regulating specific signal transduction pathways that implicate key protein effectors, such as CaMKs, MAPK/ERKs, and CREB (Figure1). Properly controlled homeostasis of this calcium signaling not only supports normal brain...
1The traditional view of calcium homeostasis is that it is maintained by two essential reactions. First, changes in extracellular Ca2+ are sensed in severa... Y Nabeshima - 《Cellular & Molecular Life Sciences Cmls》 被引量: 115发表: 2008年 Fibroblast growth factor-23: what we know, what ...
Calcium signalling: dynamics, homeostasis and remodelling Ca~(2+) is a highly versatile intracellular signal that operates over a wide temporal range to regulate many different celluar processes. An extensive Ca~(2+)-signalling toolkit is used to assemble signalling systems with very different ......
Intracellular calcium homeostasis is regulated by the calcium channels/pumps, mostly in the cell membrane and endoplasmic reticulum. In oncology, altered expressions of specific calcium channels and pumps are characteristic features of certain cancers28 and have been studied thoroughly in recent years. In...
Calcium (Ca2+) is an essential nutrient for plants and a cellular signal, but excessive levels can be toxic and inhibit growth1,2. To thrive in dynamic environments, plants must monitor and maintain cytosolic Ca2+ homeostasis by regulating numerous Ca2+ transporters3. Here we report two signalli...