In recent times, the Atangana–Baleanu–Caputo (ABC) derivative is one of the robust fractional operators to solve complex dynamical problems due to its nonlocal and non-singular Mittag–Leffler kernels. In this paper, calcium dynamics in neurons are described by a time-fractional reaction–...
To determine the impact of aging and 17β-estradiol on neuronal Ca 2+ homeostasis, intracellular Fura-2 Ca 2+-imaging was conducted during 20-pulses of glutamate in hippocampal neurons cultured from embryonic (E18), middle-age (10 months) and old (24 months) rat brain. Marked age-related ...
1991). The opposite arrangement is found in the spines of CA1 hippocampal cells where the RYRs are present in greater abundance than the InsP3Rs (Sharp et al. 1993). Calcium Signaling by the Endoplasmic Reticulum The neuronal endoplasmic reticulum network contributes to the dynamics of Ca2+ ...
Calcium imaging with genetically encoded calcium indicators (GECIs) is routinely used to measure neural activity in intact nervous systems. GECIs are frequently used in one of two different modes: to track activity in large populations of neuronal cell bodies, or to follow dynamics in subcellular ...
Kay, A. R. Inactivation kinetics of calcium currents of acutely dissociated CA1 pyramidal cells of the mature guinea-pig hippocampus.J. Physiol. (Lond.)437, 27–48 (1991).This monograph provides a comprehensive analysis of native Ca2+current inactivation in central neurons, and points to the ...
Diffusion and not active transport underlies and limits ERK1/2 synapse-to-nucleus signaling in hippocampal neurons. J. Biol. Chem. 282, 29621–29633 (2007). CAS PubMed Google Scholar Nakazawa, H. & Murphy, T. H. Activation of nuclear calcium dynamics by synaptic stimulation in cultured ...
Calcium is a major second messenger in neurons and plays a critical role in signal transduction and the regulation of many neuronal functions (Daw et al., 1993; Pulvirenti, 1992; Bar et al., 1990; Celio, 1989). Upon entering neurons, calcium ions encounter many proteins that moderate its ...
A well-known example of a conductance of this type is the delayed-rectifier potassium conductance responsible for repolarizing neurons after an action potential has fired. Some conductances have a more complicated dynamics than those just discussed. We can think of the conductances described by ...
Extrinsic signals include these growth and guidance cues and later may take the form of neuronal activity during the formation of synapses between neurons (synaptogenesis). In theory, extrinsic signals could act locally on cytoskeletal dynamics, directly changing the arborization pattern of den-drites...
We propose that transfer functions can be considered as reliable quantitative reporters to follow neurovascular coupling dynamics.doi:10.1038/s41467-020-16774-9Ali-Kemal AydinWilliam D. HaseldenYannick Goulam HoussenChristophe PouzatDavide Boido