From these results, it seems likely that the charge response of the Z-line and M-line is being mediated by titin in an anion-dependent manner. Our evidence comes from several observations. First, the similarity between the response of the Z-line potentials to the A-band potentials, where ...
In 1883, Ringer showed that to get isolated hearts to contract, it was necessary to have Ca2+ ions in the perfusion medium [421]. This was the first demonstration of the critical role of calcium in cellular activity. Remarkably, a hundred years passed be
The flow of ions into the cell is proportional to the concentration outside the cell while the flow out is proportional to the concentration inside. The energy difference between an ion of charge q outside and inside the neuron is qE when the membrane potential is E. Equilibrium of ion ...
Ion Movements in Skeletal Muscle in Relation to the Activation of Contraction The dramatic event by which skeletal muscle, when stimulated, converts chemical energy into mechanical work has fascinated and puzzled physiologists for a long time. (1) The interest with which the process of muscular act...
Ion-dependence of Z-line and M-line response to calcium in striated muscle fibres in rigordoi:10.1054/ceca.2001.0237The calcium-dependent contraction of vertebrate skeletal muscle is thought to be primarily controlled through the interaction of the thick and thin filaments. Through measurement of the...
A highly conserved calcium-binding domain, comprising two helices (E and F after the fifth and sixth helices of parvalbumin) that are linked by a short acidic calcium-binding loop that coordinates the calcium ion in a pentagonal bipyramidal arrangement. EF hands are found in many calcium-binding...
e, Tof-SIMS depth profile of various secondary ion species obtained by sputtering the recharged cathode, indicating the decomposition of CaO2 in the charge process. f, Tof-SIMS two-dimensional view images of CaO2− from the recharged cathode showing the decomposition of CaO2. Extended Data ...
In the regions around the gas–liquid interfaces of CO 2/NH 3 microbubbles, Ca 2+ and CO 3 2 ion concentrations can be adjusted because of the characteristic of the electric charge on the bubble surface and the decrease in CO 2 concentration based on unit bubble caused by minimization of ...
Focuses on the calcium ion, Ca2+, as a signalling agent in the human body. How the ion acts during cell birth, life, and death; How it regulates cellular p... Berridge,Michael,J.,... - 《Nature》 被引量: 2562发表: 1998年 Prostaglandins stimulate calcium-dependent glutamate release in...
The inside-out patches were excised and, when they showed no activity of intrinsic ion channels, αS channels were incorporated into the membrane by applying external voltage pulses as described previously18. The experiments were done when only one channel was inserted into excised patches. This ...