Using an intracellular dialysis technique a study was made on calcium and sodium inward currents at the neuroblastoma somatic cell membrane in suspension and during the course of artificial morphological differentiation produced by raising the pH of the culture medium to 8.0–8.2. The density of ...
来自 Springer 喜欢 0 阅读量: 37 作者: WA Catterall 摘要: Sodium channels Electrical signals control contraction of muscle, secretion of hormones, sensation of the environment, processing of information in the brain, and output from the brain to peripheral... 被引量: 105 ...
Childs GV, Marchetti C, Brown AM (1987 b) Involvement of sodium channels and two types of calcium channels in the regulation of adrenocorticotropin release. Endocrinology 120:2059–2069Childs GV , Marchetti C & Brown AM ( 1987 ). Involvement of sodium channels and two types of calcium ...
Voltage gated Na channels comprise a gene family consisting of 9 different subtypes (NaV1.1-NaV1.9). As shown in Table A, these subtypes show tissue specific localization and functional differences (See, Goldin, A. L. (2001) “Resurgence of sodium channel research” Annu Rev Physiol 63: 871...
Lidocaine block of cardiac sodium channels. J Gen Physiol 81: 613–642, 1983 PubMed CAS Google Scholar Beaty GN and Stefani E. Calcium dependent electrical activity in twitch muscle fibres of the frog. Proc R Soc Lond B Biol Sci 194: 141–150, 1976 PubMed CAS Google Scholar Bech-...
Glial and neuronal isoforms of Neurofascin have distinct roles in the assembly of nodes of Ranvier in the central nervous system Rapid nerve impulse conduction in myelinated axons requires the concentration of voltage-gated sodium channels at nodes of Ranvier. Myelin-forming oligoden... B Zonta,...
Sodium/calcium exchange in smooth-muscle microsomal fractions. (1984): Sodium/calcium exchange in smooth-muscle microsomal fractions. Biochem. J. 218,421-427MOREL, N., AND T. GODFRAIND. Sodium-calcium exchange ... N Morel,T Godfraind - 《Biochemical Journal》...
The latter has been the main area for trials and use of drugs that modulate ion channels such as carbamazepine and gabapentin, but given the large peripheral drive that follows tissue damage, there is a clear rationale for blocking voltage gated sodium and calcium channels in these pain states....
Bezanilla F (2000) The voltage sensor in voltage-dependent ion channels. Physiol Rev 80(2):555–592 Article CAS PubMed Google Scholar Bhattacharjee A, Joiner WJ, Wu M, Yang Y, Sigworth FJ, Kaczmarek LK (2003) Slick (Slo2.1), a rapidly-gating sodium-activated potassium channel inhibited...
Sodium ion channel mutations in glioblastoma patients correlate with shorter survival Mol. Cancer, 10 (2011), p. 17, 10.1186/1476-4598-10-17 View in ScopusGoogle Scholar [5] A.D. Joshi, D.W. Parsons, V.E. Velculescu, G.J. Riggins Sodium ion channel mutations in glioblastoma patients...