Ergocalciferol versus calcitriol for controlling chronic kidney disease mineral bone disorder in stage 3 to 5 CKD:A randomized controlled trial. Zhang D,Li H,Yin D,et al. European Journal of Pharmacology . 2016Zhang D, Li H, Yin D, et al. Ergocalciferol versus calcitriol for controlling ...
The presence of 1α-hydroxylase in prostate cells and the paracrine anti-proliferative actions of locally synthesizedcalcitriol[376,377]raise the possibility that increasing the circulating concentrations of 25(OH)D by dietary administration of precursor vitamin D2(ergocalciferol) or vitamin D3(cholecalc...
pharmacologic doses of vitamin D and its derivatives should be withheld during calcitriol treatment to avoid possible additive effects and hypercalcemia. If treatment is switched from ergocalciferol (vitamin D2) to calcitriol, it may take several months for the ergocalciferol level in the blood to ...
Pregnancy Category C. Calcitriol has been found to be teratogenic in rabbits when given at doses of 0.08 and 0.3 mcg/kg (approximately 2 and 6 times the maximum recommended dose based on mg/m2). All 15 fetuses in 3 litters at these doses showed external and skeletal abnormalities. However...
[2]. Rambeck et al (1984) Biological activity of 1 alpha,25-dihydroxyergocalciferol in rachitic chicks and in rats. Int.J.Vitamin.Nutr.Res. 54 135. [3]. Shamik J. Parikh, Marni Edelman, Gabriel I. Uwaifo et al. The Relationship between Obesity and Serum 1,25-Dihydroxy Vitamin D Conc...
Calcitriol also enhances phosphorus absorption along the entire small intestine, but principally in the jejunum and ileum. The activated forms of ergocalciferol, doxercalciferol, and cholecalciferol may have a negative feedback effect on parathyroid hormone (PTH) production.|Calcitriol appears to act in...
Alfacalcidol, calcitriol, and dihydrotachysterol are usually preferred in patients with renal failure since these patients have impaired ability to synthesize calcitriol from cholecalciferol and ergocalciferol; therefore, the response is more predictable. In addition, their shorter half-lives may make ...
(excessive) sun exposure.49Different types of natural vitamin D sterols are to our availability: ergocalciferol, cholecalciferol, 25(OH)2D, and calcitriol. The first synthetic vitamin D was already produced for patients with rickets in 1927 by Merck and Bayer, but only became part of the ...
Susantitaphong P, Nakwan S, Peerapornratana S, et al. A double-blind, randomized, placebo-controlled trial of combined calcitriol and ergo- calciferol versus ergocalciferol alone in chronic kidney disease with proteinuria. BMC Nephrol. 2017;18(1):19....
Susantitaphong P, Nakwan S, Peerapornratana S, et al. A double-blind, randomized, placebo-controlled trial of combined calcitriol and ergo- calciferol versus ergocalciferol alone in chronic kidney disease with proteinuria. BMC Nephrol. 2017;18(1):19....