Ectopic calcification of blood vessels, heart valves, and skeletal muscle is a major clinical problem. There is now good evidence that angiogenesis is asso... Collett,DM G. - 《Circulation Research》 被引量: 427发表: 2005年 Mitigation of ectopic calcification in osteopontin-deficient mice by exo...
Based on the observed occurrence of reamputation in association with normal or elevated leg-brachial ratios, it appears that a Doppler pressure index above 0.90 is not a reliable indicator of adequate blood flow in severe diabetic occlusive arterial disease....
Further studies are required to comprehensively establish AR expression levels throughout the different layers of arterial blood vessels. The ability of DHT to replicate the effects of testosterone, together with our data revealing a lack of aromatase expression, suggests that the pro-calcificatory ...
Calcium phosphate bions (CPB) are biomimetic mineralo-organic nanoparticles which represent a physiological mechanism regulating the function, transport and disposal of calcium and phosphorus in the human body. We hypothesised that CPB may be pathogenic
Peripheral arterial' disease (PAD) in type 1 diabetes can include occlusive changes in leg blood pressure due to atherosclerotic plaques and manifest as a low ankle brachial index (ABI). Alternatively, advanced calcification with non-compressible vessels may manifest as a high ABI. To determine ...
Vascular calcification is the abnormal deposition of calcium phosphate complexes in blood vessels, which is regarded as the pathological basis of multiple cardiovascular diseases. The flowing blood exerts a frictional force called shear stress on the vascular wall. Blood vessels have different hydrodynamic...
approximately 50% of patients with CKD have coronary artery stenosis, regardless of the presence or absence of symptoms and/or signs [7]. One characteristic pathophysiologic feature of atherosclerosis in CKD patients is combined injuries of intima and media in vessels, i.e., endothelial dysfunction...
CAD can easily misclassify parenchyma, connective tissue, and blood vessels as breast lesions, vascular calcifications, and axillae as microcalcifications. Because of its low specificity and high false-positive rate, CAD should not be used alone in mammography for breast examinations [15]. Deep ...