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The range of CAG repeats of TBP gene is 31- 42 in normal population and 43 - 63 in SCA17 patients.To investigate the TBP trinucleotide expansion effect on neurodegeneration, we conducted genotyping analysis in both normal and neurodegenerative disease populations in Taiwan. We found that the ...
Complete Ionic Equation The complete (or total) ionic equation includes spectator ions. Write it by breaking all the soluble ionic compounds into their respective ions. Make sure that any subscripts are moved into the coefficient of the resulting ions and no atoms are lost. ...
Complete Ionic Equation The complete (or total) ionic equation includes spectator ions. Write it by breaking all the soluble ionic compounds into their respective ions. Make sure that any subscripts are moved into the coefficient of the resulting ions and no atoms are lost. ...
The Cag Type IV secretion system, which contributes to inflammation and cancerogenesis during chronic infection, is one of the major virulence factors of the bacterial gastric pathogen Helicobacter pylori. We have generated and characterized a series of non-marked site-directed chromosomal mutants in ...
CONCLUSION The presentation of cagA and cagM were predominant in Chinese H.pylori strains, but cagA and cagM in cag Ⅰ could be lost separately. It is suggested that there are some new mechanisms to split cag Ⅰ and, moreover, to delete cag Ⅰ partially. 展开 ...
However, in the absence of SbcCD and of proofreading by DnaQ this bias was lost. This suggested that the bias towards large deletions for the CTG leading strand orientation was influenced by SbcCD but was less easily explained by secondary structure formation given that the single-strands ...
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and are found mostly in individuals with early/more severe disease. Of the seven individuals with late/less severe HD but carrying FAN1 R377W or R507H, one had an extra CAACAG in the expandedHTTrepeat tract. Five were also genotyped in GeM-HD GWAS8: one was homozygous and two were ...
As shown in Figure 3B, JO1 mice lost the ability to escape tail suspension by 18 weeks, an age when wild-type mice usually escaped. To derive statistically meaningful comparisons, mice were classified as tending to escape if they escaped at least once in five trials (the minimum number of ...