The role of the chromatin assembly complex (CAF-1) and its p60 subunit (CHAF1b) in homeostasis and disease. Biochim Biophys Acta 2015;1849: 979-86. https://doi.org/10.1016/j.bbagrm.2015.05.009.The role of the chromatin assembly complex (CAF-1)and its p60subunit (CHAF1b)in ...
Given the effect of the CAF-1 complex on chromatin accessibility in these and other cellular paradigms14,15,16, CAF-1 has been viewed as a general stabilizer of cell identity that prevents cells from adopting an open chromatin state characteristic of immature cells. However, studies of CAF-1 ...
More and more studies have analyzed the structure and biological function of the CAF-1 complex,and found that CAF-1 plays an important role in the process of somatic cell reprogramming. Therefore , this paper focuses on the structure , biologicalfunctionandtheroleofCAF-1insomaticce l ...
Nonetheless, the direct contribution of this subunit to histone binding in the context of the full CAF-1 complex has not yet been tested. In cells, histones are handed off to CAF-1 by the histone chaperone ASF1, which directly interacts with the C-terminal region of the CAF-1 middle ...
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caf1蛋白;高活性;caf1 protein 纯度::Greater than 90% as determined by SDS-PAGE. 基因名::CNOT8 Uniprot No.::Q9UFF9 别名::CAF 1; CAF 2; CAF1; CAF1 like protein; CAF1-like protein; CAF2; CALIF; CALIFp; CCR4 associated factor 8; CCR4 NOT transcription complex subunit 8; CCR4-associ...
Here, we characterize the role of the plant orthologs HISTONE REGULATOR A (HIRA), UBINUCLEIN (UBN) and CAlcineurin BINding protein 1 (CABIN1) constituting the HIR complex. Arabidopsis loss-of-function mutants for the different subunits of the complex are viable but present reduced fertility in ...
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CNOT7 (CCR4-NOT Transcription Complex, Subunit 7, CAF1, hCAF-1) (MaxLight 405) 中文名: 中文别名: CBNumber: CB04929732 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商1 CNOT7 (CCR4-NOT Transcription Complex, Subunit 7, CAF1, hCAF-1) (MaxLight 405)化学性质 ...
在植物中,转录抑制作用的PcG蛋白通过形成如PRC1(polycomb repressive complex 1) 和PRC2在内的多亚基蛋白复合物,其中PRC2发挥在靶基因调节下催化组蛋白H3赖氨酸27的三甲基化(H3K27me3)的作用,作为PCR1的重要组分LIKE HETEROCHROMATIN PROTEIN 1(LHP1)通过MSI1的作用识别H3K27me3位点,发挥抑制FLC(flowering locus ...