CACNA1I was the only gene in this cohort to harbor missense variations in more than one proband31. The resulting amino acid alterations, T797M and R1346H (numbered according to NM_021096 but equivalent to R1311H NM_00100340631), are predicted to reside in extracellular regions of domains ...
This is attributed to the chemical bond strength, defined as the ratio of the valence over the internuclear distance; the chemical bond of Mg–O (1.09) is larger than that of Cu–O (1.01). The obtained results are in accordance with the results reported by other authors [24]. Extending...