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This report describes experiments demonstrating that CREB or a closely related protein mediates Ca2+-dependent regulation of BDNF, a neurotrophin that modulates synaptic activity. In cortical neurons, Ca2+ influx triggers phosphorylation of CREB, which by binding to a critical Ca2+ response element (...
Thus, DQ-Green-BSA beads report proteolytic activity in the phagosome by a gain of DQ-Green fluorescence signal (Fig. 5a), which is presumably derived from lysosomal proteases. WT and KO BMDMs were incubated with DQ-Green- BSA-labelled beads, and the fluorescence was measured by flow ...
A report of novel STIM1 deficiency and 6-year follow-up of two previous cases associated with mild immunological phenotype. J Clin Immunol. 2019;39:249–56. Article Google Scholar Hajnóczky G, Csordás G, Madesh M, Pacher P. Control of apoptosis by IP(3) and ryanodine receptor driven...
Mag-fura-2 (also called furaptra) and mag-indo-1 were originally designed to report intracellular Mg2+ levels (Fluorescent Mg2+ Indicators—Section 19.6); however, these indicators actually have much higher affinity for Ca2+ than for Mg2...
We are the first to report derivation of human iPSCs from ASD patients carrying NRXN1α+/−. The cortical excitatory neurons from NRXN1α+/− iPSCs displayed a novel phenotype of increased frequency, duration, and amplitude of Ca2+ transients. This is supported by transcriptome analyses, ...
Cellular mechanisms of epilepsy: a status report. Science 1987; 237: 157–164. Article PubMed CAS Google Scholar Pfyffer GE, Faivre-Baumann A, Tixier-Vidal A et al. Developmental and functional studies of parvalbumin and calbindin D28k in hypothalamic neurons grown in serum-free medium. J ...
Due to its superior sensitivity, R-GECO1 is able to report flg22- and chitin-induced Ca2+ signals on a cellular scale, which allowed identification of defined [Ca2+]cyt oscillations in epidermal and guard cells in response to the fungal elicitor chitin. Moreover, we discovered that flg22- ...
Block or Report Popular repositoriesLoading PlayinHUSTPlayinHUSTPublic a project "PlayinHUST" website which offer a platform of entertainment in HUST CSS12 hust-ca2.github.iohust-ca2.github.ioPublic CSS3 4 contributions in the last year ...
Here we report that 3-OH-GA activated recombi- nant NMDA receptors (e.g. NR1/NR2A) but not recombinant ␣-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptors (e.g. GluR-A/GluR-B) in HEK293 cells. Fluorescence micros- copy using fura-2 as Ca2ϩ indicator revealed that 3-OH...