Taken together, we suggest that Ca2ϩ influx is modulated by Naϩ in 3-OH-GA-induced cell damage. Inhibition of the respiratory chain can impair the ability of neurons to maintain normal resting membrane potential due to ATP depletion and can decrease the activity of Naϩ/Kϩ- ATPase...
Figure 1. The speed of synaptic transmission is increased with development at the calyx of Held/MNTB synapse. A1, A2, Presynaptic stimulation protocol. Top, The presynaptic potential was depolarized to 70 mV for 2 ms, followed by 0 mV for 1, 3, 5, 10, 20, 30, and 50 ms. The durat...
ca2 is a powerful, all-purpose, cross-platform C++ framework and library suite that enables developers to build exceptional user experiences by harnessing the full potential of the C++ language. Its flexible architecture and abstractions facilitate the rapid development and deployment of complex, perform...
The molecular mechanism of the termination of insect diapause, part 1: A timer protein, TIME-EA4, in the diapause eggs of the silkworm Bombyx mori is a met... TIME-EA4 is an ATPase that measures time intervals, functioning as a diapause duration clock in diapause eggs of the silkworm, Bo...
Thus, the expression pattern for the hCaCC sub- types in the nasal mucosa is identical to that in the trachea (31, 32). Furthermore, semiquantitative (multiplex) RT-PCR was performed on RNA isolated from nasal tissues of eight healthy and six CF individuals. Either hCaCC-2 or hCaCC-3...
An enhanced NCX function in FTG, as reflected by an accelerated relaxation of the caffeine-induced Ca2+ transient, is insufficient to maintain a normal diastolic Ca2+ during high rates of stimulation. Although a high SR Ca2+ release following excitation is maintained, the hypercontractile state ...
Mfn2 expression is reduced in H/R-treated NRK-52E cells and renal tissue of I/R rats. At the cellular level, overexpression of Mfn2 promoted cell proliferation, inhibited cell apoptosis, attenuated mitochondrial damage and Ca2+ overload, and ER stress. In addition, Mfn2 also restored the ...
摘要: Determines whether or not cellular metabolism in cytosolic free magnesium and calcium in platelets of patients with vasospastic angina is abnormal. Examination of platelet aggregation; Acceleration of calcium influx in plasma membrane.年份: 1998 ...
IAV infection is a complex, multistep process. In the initial step (adsorption), the virus attaches to a host cell through binding of its major surface protein, haemagglutinin (HA), to sialylated cell surface proteins. In the second step (internalization or entry), the adhered viral particle ...
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a high co-morbidity of epilepsy and associated with hundreds of rare risk factors. NRXN1 deletion is among the commonest rare genetic factors shared by ASD, schizophrenia, intellectual disability, epilepsy, and developmental delay. ...