【Ca2+】一图记牢钙通道阻滞剂 钙拮抗剂(Calcium Antagonists ),也叫钙通道阻滞剂(Calcium Channel Blockers),主要通过阻断心肌和血管平滑肌细胞膜上的钙离子通道,抑制细胞外钙离子内流,使细胞内钙离子水平降低而引起心血管等组织器官功能改变的药物。临床常用的有硝苯吡啶...
Synonyms Ca 2+ channel antagonists Definition Ca 2+ is an important intracellular second messenger that controls cellular functions including muscle contraction in smooth and cardiac muscle. Ca 2+ channel blockers inhibit depolarization-induced Ca 2+ entry into muscle cells in the cardiovascular system...
中文名：伊拉地平;地拉平;L型Ca2+通道阻滞剂 英文名：Isradipine, L-type Ca2+ channel blocker;CAS号：75695-93-1 结构式：CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)c2cccc3c2non3)C(=O)OC 分子式：C19H21N3O5 分子量：371.39 闪点 ：257.4±32.9 °C 沸点：501.9±60.0 °C at 760 mmHg ...
中文名：盐酸维拉帕米;L型Ca2+通道阻滞剂;英文名：(±)-Verapamil hydrochloride;Verapamil hydrochloride;L-type Ca2+ channel blocker;Izoptin Hydrochloride;Verogalid ER;Veraptin;Vasolan;NSC 272366; CAS号：152-11-4 结构式：CC(C)C(CCCN(C)CCc1ccc(c(c1)OC)OC)(C#N)c2ccc(c(c2)OC)OC.Cl 分子...
中文名：尼群地平;硝苯乙吡啶;L型Ca2+通道阻滞剂 英文名：Nitrendipine, L-type Ca2+ channel blocker CAS号：39562-70-4 结构式：CCOC(=O)C1=C(NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC)C)C 分子式：C18H20N2O6 分子量：360.36 闪点：249.5±28.7 °C 沸点：488.9±45.0 °C at...
Nifedipine(硝苯地平)是一种L型Ca2+通道阻滞剂，一种强效、长效的血管扩张剂。Nifedipine还显示出抑制血管炎症。图1.Nifedipine(硝苯地平)化学结构 Nifedipine(硝苯地平)基础信息 中文名：心痛定；硝苯吡啶；利心平；硝苯地平，L 型 Ca2+ 通道阻滞剂；英文名：Nifedipine;L-type Ca2+ channel blocker CAS号：...
Dotarizine/ a representative of Ca2+ channel blockers from diphenilbutilpiperazines group also reveals antiserotoninergic 5-HT2A and 5-HT2C receptorspecific properties. The vasodilatatory and antivasoconstrictive properties of this compound were reported previously. In this study the efficacy of ...
PD 173212是一种选择性 N 型电压敏感钙通道 (VSCC) 阻断剂，在 IMR-32 测定中的 IC50 为 36 nM。图1.PD 173212化学结构 PD 173212基础信息 产品名：PD173212;PD 173212;N-type voltage-gated Ca2+ channel blocker;N-type voltage sensitive calcium channel;N型电压门控Ca2+通道阻滞剂;N-型电压敏感性钙...
Nimodipine （尼莫地平）基础信息 中文名：尼莫地平；(±)-4-(3-硝基苯基)-2,6-二甲基-1,4-二氢吡啶-3,5-二羧酸甲氧基乙基酯异丙酯;尼莫替丁 英文名：Nimodipine；L-type Ca2+ channel blocker CAS号：66085-59-4 结构式：CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)c2cccc(c2)[N+](=O)[O-])C...
Ca2+ signalling in fibroblasts and the therapeutic potential of KCa3.1 channel blockers in fibrotic diseasesThe role of Ca2+ signalling in fibroblast physiology is of great interest, particularly in fibrosis鈥恟elated diseases. Intracellular free Ca2+ ([Ca2+]i) in mammalian cells is a ubiquitous ...