Administration of CA102N in PANC-1 xenografts resulted in a dose-dependent and statistically significant decrease in tumor growth at 9.8 mg/kg and 14.7 mg/kg Nim equivalents, respectively, compared to the vehicle control group. A significant decrease (80%) in liver metastasis was also noted in...
CA102N (50 mg/kg and 200 mg/kg) i.v. injected mice carrying CT26 mouse colon tumor showed significantly reduced average tumor weight (726.1 卤 335.2 mg and 633.4 卤 453.5 mg, respectively) compared to that of the vehicle control treated mice (1392.0 卤 523.8, p < 0.05). The reduction...
Introduction: CA102N is a novel anticancer drug developed by covalently linking H-Nim (N-(4-Amino-2-phenoxyphenyl methanesulfonamide) to Hyaluronic Acid to target CD44 receptor-rich tumors. The proposed approach seeks to enhance the efficacy and overcome limitations as...
CA102N (50 mg/kg and 200 mg/kg) i.v. injected mice carrying CT26 mouse colon tumor showed significantly reduced average tumor weight (726.1 ± 335.2 mg and 633.4 ± 453.5 mg, resectively) comared to that of the vehicle control treated mice (1392.0 ± 523.8, < 0.05). The reduction of...
目的 应用实时三平面定量组织速度成像(Triplane-QTVI)技术定量评价左心室不同透壁程度梗死心肌节段心内,外膜下心肌运动情况.方法 对26例非ST段抬高型心肌梗死(NSTMI)患者(A组),39例ST段抬高型心肌梗死(STMI)患者(B组)及25名健康志愿者(正常组)采集实时三平面组织速度图像,测量左心室梗死心肌节段收缩期心内膜下...
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Characterization of CA102N, a hyaluronic acid drug conjugate for the treatment of colorectal cancerThe expression of phase I and II biotransformation enzymes was examined with respect to experimental diet composition and with the addition of the bi-functional inducer Xavone. Enzymatic activity and mRNA...
In Vitro and In Vivo Evaluation of the Anti-tumor Activity of CA102N, A Novel Hyaluronic Acid Conjugated Drug (HACD), Against Colorectal CancerEskouhie Tchaparian
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钢琴曲《谷粒飞舞》,音乐语言简洁朴素,生动活泼,极富中国民族艺术特色,是一首深受广大钢琴演奏者喜爱的优秀钢琴作品。本文针对《谷粒飞舞》的曲式调性、作曲技术、演... 刘雪颖 - 《中国校外教育》 被引量: 6发表: 2010年 浅谈钢琴曲《谷粒飞舞》的教学研究 钢琴曲《谷粒飞舞》,音乐语言简洁朴素,生动活泼,极富...