与之前的报告类似,大多数(14/15)表现出IH电流的复原细胞具有水平方向的树突区域,且局限于Oriens层(s.o.),而所有三个没有表现出IH电流的复原细胞的树突都延伸到了放射层(stratum radiatum)。从图1的原始记录轨迹可以看出,施加100微摩尔每升的拉莫三嗪(LTG)在5–7分钟内导致IH电流明显增加(所示数据是在开始灌流...
Kovalenko, T, Osadchenko, I, Nikonenko, A, Lushnikova, I, Voronin, K, Nikonenko, I, Muller, D, Skibo, G (2006) Ischemia-induced modifications in hippocampal CA1 stratum radiatum excitatory synapses. Hippocampus 16: pp. 814-825Kovalenko T, Osadchenko I, Nikonenko A, Lushnikova I, ...
(A) Representative images of presynaptic boutons in the CA3–CA1 stratum radiatum in control and Caps1 cKO mice. The presynaptic bouton is coloured in purple (scale bar: 200 nm). (B) Number of SVs in control and Caps1 cKO synapses; n = 48 and 51 synapses for control and Caps1 ...
Yellow arrows indicate labeled neurons at the border of stratum radiatum (SR) and lacunosum-moleculare (SLM). Pyr: pyramidal layer. All images were captured using the same light intensity, and displayed with identical brightness and contrast settings. Repeated on 3 different mice. b, For ...
By electron microscopy, the spine shape and density of synapses within stratum radiatum was not significantly different between the two groups, however, the total combined length of post-synaptic densities (PSDs) per test field (117µm²) was significantly less in PNEE rats (2157 ±121 nm...
the fact that we did not observe population spikes at high stimulus intensities argues against the idea that there is a subpopulation of ‘displaced’ pyramidal neurones whose cell bodies are located in the stratum radiatum. Thus, based on visual inspection, biochemical staining and ...
Comparisons revealed that Boswellia -treated aged rats had greater volumes than control animals in stratum pyramidale and stratum radiatum lacunosum-moleculare. The neurons of CA1 in experimental rats had more dendritic segments (40.25卤4.20) than controls (30.9卤4.55), P =0.001. The total ...
collaterals to CA1 stratum radiatum in slices (no statistic difference at P<0.05). 5 华中科技大学硕士学位论文 Conclusion: 1. Clonidine and yohimbine could modulate the synaptic transmission efficiency in LTP from Schaffer collaterals to hippocampal CA1 stratum radiatum ...
Extracellular evoked field excitatory postsynaptic potentials (fEPSPs) were recorded in the stratum radiatum of the CA1 area of the slice at 28–35 days of age. Our results indicate that a significant difference existed in the magnitude of LTP between the control group and MS180 group, but ...
successive actions of distinct interneuron circuits during repetitive stimulation of Schaffer collaterals [83]. In this study it was shown that application of a short stimulation train of pulses to CA1 stratum radiatum first elicits a strong somatic inhibition and then inhibition shifts towards more ...