Cardiomyocyte-specific expression of IKK2-CA leads to defects in compact zone formation.Bärbel, KrautHarald, J. MaierEnikö, KókaiKatja, FiedlerThomas, BoettgerAnnett, IllingSawa, KostinPaul, WaltherThomas, BraunThomas, Wirth
方法:测量 培养的人角膜基质成纤维细胞在基础状态下及脂多糖作用下分泌白细胞介素 1、肿 瘤坏死因子 α、白细胞介素 6、白细胞介素 8 水平以及 IKK-2 受体阻滞剂(TPCA1)、地塞米松干预后的变化,检测细胞表面细胞间黏附分子 1 及细胞内白细胞介素 6 表达水平,从 mRNA 水平验证细胞间黏附分子 1、白细胞介素...
Summary Constitutive Kras and NF-κB activation is identified as signature alterations in pancreatic ductal adenocarcinoma (PDAC). However, how NF-κB is activated in PDAC is not yet understood. Here, we report that pancreas-targeted IKK2/β inactivation inhibited NF-κB activation and PDAC developm...
董锦目前担任山西硕克斯商贸有限公司法定代表人,同时担任山西硕克斯商贸有限公司执行董事兼总经理;二、董锦投资情况:董锦目前是山西硕克斯商贸有限公司直接控股股东,持股比例为100%;目前董锦投资山西硕克斯商贸有限公司最终收益股份为100%;三、董锦的商业合作伙伴:基于公开数据展示,董锦与董金虎为商业合作伙伴。
而在美联储下半年存在1~2次降息的预期下,下半年国内降息是大概率事件,而降息方式可能是直接下调公开市场政策利率,或通过推行利率并轨的方式下调LPR利率并传导至贷款利率,最终仍是实现实质降息。我们认为近期10年期国债收益率仍将在3.0-3.4%区间运行。若有外部利率环境和国内利率并轨的进一步利好举措则收益率将迎来向下...
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IKK2ca expression in vivo dampens expression of chondrogenic and osteogenic markers.Gaurav, SwarnkarKaihua, ZhangGabriel, MbalavieleFanxin, LongYousef, AbuAmer
Indole carboxamide compounds of Formula (I): are provided as inhibitors of kinase activity, in particular IKK2 activity as well as compositions and medicaments containing them, for use in inflammatory and tissue repair disorders.PAUL BAMBOROUGH...
The expression level of NKX2-1 messenger RNA was negatively associated with the extent of SOD immunostaining and the IKKβ messenger RNA expression level in lung tumors. The extent of SOD2 immunostaining and IKKβ messenger RNA levels may independently predict overall survival and relapse-free ...
Expression of IKK2ca impedes bone formation and reduces bone mineral density.Gaurav, SwarnkarKaihua, ZhangGabriel, MbalavieleFanxin, LongYousef, AbuAmer