Cyclin T is a partner for CDK9, an RNAPII transcription elongation factor. Remarkably, the interaction of Tat with cyclin T strongly enhances the affinity and specificity of the Tat:TAR RNA interaction, and confers a requirement for sequences in the loop of TAR that are not recognized by Tat...
pch1 +, a Second Essential C-type Cyclin Gene in Schizosaccharomyces pombe The gene(cyclinomology) was isolated in a two-hybrid screen for proteins that interact with Cdc2. The cyclin box region of Pch1 protein shares greatest seq... Furnari,A B. - 《Journal of Biological Chemistry》 被...
Expression of cyclin-dependent kinase inhibitors in vascular disease Arterial lesions in cardiovascular diseases are characterized by proliferation and migration of smooth muscle cells as well as deposition of connective tis... FC Tanner,ZY Yang,E Duckers,... - 《Circulation Research》 被引量: 818...
(1997) Stress and developmental regulation of the yeast C-type cyclin Ume3p (Srb11/ Ssn8p). EMBO J., 16, 4665±4675.Cooper KF, Mallory MJ, Smith JB,Strich R (1997). Stress and developmental regulation of the yeast C-type cyclin Ume3p (Srb11p/Ssn8p). EMBO J 16, 4665-4675....
BDCA2, blood DC antigen 2 protein; BLNK, B cell linker; BTK, Bruton's tyrosine kinase; CARD9, caspase‑recruitment domain member 9; CDC42, cyclin‑dependent kinase 42; CLEC, C‑type lectin domain family member; CLR, C‑type lectin receptor; CXCL2, CXC‑chemokine ligand 2; DC,...
the oocyte itself can also produce cAMP due to activation of the constitutively active heterotrimeric G protein (Gs)-linked receptors GPR3 or GPR12, which primarily induces meiotic arrest via protein kinase A (PKA)-mediated phosphorylation of the proteins that regulate cyclin dependent protein kinases...
Cyclin-dependent kinase 5 (Cdk5) is ubiquitously expressed, proline-directed, serine/threonine kinase with diverse substrates. The physiologic activity of Cdk5 is essential for normal neuronal development and immune activation. Allogeneic HCT with Cdk5-deficient donors resulted in significantly l...
James CG, Woods A, Underhill TM, Beier F: The transcription factor ATF3 is upregulated during chondrocyte differentiation and represses cyclin D1 and A gene transcription. BMC Mol Biol. 2006, 7: 30-10.1186/1471-2199-7-30. Article PubMed Central PubMed Google Scholar Chikuda H, Kugimiya ...
We recently proposed a detailed model describing the dynamics of the network of cyclin-dependent kinases (Cdks) driving the mammalian cell cycle (G茅rard a... C Gérard,A Goldbeter - 《Frontiers in Physiology》 被引量: 36发表: 2012年 Electrical properties of polyunsaturated natural products: fi...
图1,2 组合性套细胞淋巴瘤伴经典型霍奇金淋巴瘤的组织学,图1 淋巴结结构破坏,呈结节状生长 HE 低倍放大;图2 炎性病变背景内可见散在R-S细胞 HE 高倍放大图3 套细胞淋巴瘤cyclin D1核阳性表达 SP法 高倍放大图4 经典霍奇金淋巴瘤R-S细胞CD30膜表达阳性 SP法 高倍放大 病理诊断:组合性套细胞淋巴瘤合...