进入细胞核由至少两种核定位信号控制:一种是最有可能利用核导入受体Impβ1的常规基本核定位信号,另一种是位于需要核导入转运蛋白1的蛋白质N端部分的非常规核定位信号。有趣的是,这主要涉及单体c-Fos,并在与Jun蛋白异二聚时受到抑制。这表明二聚化是重要的,不仅对...
Ju1.200925(4)405～411神经解剖学杂志(ChineseJournalofNeuroanatomy)c—Fos和FosB/△FosB蛋白在精神分裂症模型小鼠脑内表达的差异①马传..
进入细胞核由至少两种核定位信号控制:一种是最有可能利用核导入受体Impβ1的常规基本核定位信号,另一种是位于需要核导入转运蛋白1的蛋白质N端部分的非常规核定位信号。有趣的是,这主要涉及单体c-Fos,并在与Jun蛋白异二聚时受到抑制。这表明二聚化是重要的,不仅对于活性AP-1转录复合物的形成,而且对于将它们保持...
大鼠短暂脑缺血后海马区c-fos mRNA和FOS蛋白表达时间规律.pdf,督钓伍组蛊龄对咋倪厚豢穆茶灰忙寝孵展豢狰骋甸啼驯角熬仕秋详瑶锰桨验暮揉纬土舞锋陕斋辅惫足吉眯鸣鳞氟著氛妻身蔷祟嗓滴才焊粗详窒饭屉援
背景资料The Fos gene family consists of 4 members:FOS,FOSB,FOSL1,and FOSL2.These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family,thereby forming the transcription factor complex AP-1.As such,the FOS proteins have been implicated as regulators of cell proli...
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Background:The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins...
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原文献: c-Fos and neuronal plasticity: the aftermath of Kaczmarek’s theoryc-Fos基因属于IEG(immediate early gene)的一类,是原癌基因的一种。 c-Fos最早被注意到是因为其在注射谷氨酸或去甲肾上腺素,甚…
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell...
Kainic acid-induced neuronal damage is associated with DNA damage and a unique immediate-early gene response in H c-fos-lac ZH transgenic rats Previously, we established that persistent upregulation of c-fos expression preceded kainic acid (KA)-induced neuronal death in mice. To discriminate betwe...