Under a Creative Commons license open accessMetabotropic glutamate receptors (mGlu receptors), the Ca2+-sensing receptor, γ-aminobutyric acid type B receptors, and one group of pheromone receptors constitute a unique family (also called family 3) of heptahelical receptors. This original family shares...
3.2.2.2 The P5B C-terminus The C-terminus of ATP13A2 and Ypk9 forms a short helix, which interacts with the [P] domain mainly by hydrophobic interactions [90–94], but its functional role is not yet resolved. The C-terminus of ATP13A2 seems to be critical for its catalytic activity,...
免 疫 原 KLH conjugated synthetic peptide derived from human LAMR1 C-terminus 亚 型 IgG 纯化方法 affinity purified by Protein A 储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:...
BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein. Production of amyloid-beta protein (Abeta) is initiated by a beta-secretase that cleaves the Abeta precursor protein (APP) at the N terminus of Abeta (the...
The β amyloid protein found in extracellular deposits in Alzheimer's disease (AD) is heterogeneous at its C-terminus; proteins ending at residues 40, 42, and 43 have been identified in neuritic deposits, while protein in vascular amyloid appears to end at residue 39 or 40. Studies of synthe...
We show that the fission yeast dis2 protein phosphatase, which is highly similar to mammalian type 1 phosphatase, is a phosphoprotein containing phosphoser... Yamano,Ishii,Yanagida - 《Embo Journal》 被引量: 191发表: 1994年 The C Terminus of the Escherichia coli RecA Protein Modulates the DNA...
免疫原:KLH conjugated synthetic peptide derived from human CK18 C-terminus 保质期:详见说明书 标记物:详见说明书 包装规格:0.1ml/100μg0.2ml/200μg 抗原来源:Rabbit 适应物种:详见说明书 克隆性:否 标识物:详见说明书 形态:详见说明书 保存条件:Store at -20 °C for one year. Avoid repeated freeze...
Aggregation of the 140-residue protein α-synuclein (αSN) is a key factor in the etiology of Parkinson’s disease. Although the intensely anionic C-terminal domain (CTD) of αSN does not form part of the amyloid core region or affect membrane binding ability, truncation or reduction of cha...
In addition, EcR is degraded by the peptidyl-dipeptidase cathepsin B (CatB) and the endopeptidase cathepsin S (CatS) at the C-terminus in an isoform-specific manner, despite identical C-termini. Ubiquitin-proteasome-mediated degradation and the proteolytic action are modulated by heterodimerization ...
terminus ofEcMinC, we studied its effect on cell morphology and cell growth, revealing thatAahelix3 impaired normal cell division inE. coli. Results of a co-pelleting assay and binding free energy calculation further led to our conclusion that theAahelix3 enhances the interaction ofAaMinCD ...