In this work, we introduce hyperpolarized, 13C-labelled [1,5-13C2]Z- 4-methyl-2-oxopent-3-enedioic acid (Z-OMPD) as a probe for simulta- neous 3D imaging of renal perfusion and filtration and 2D imaging of pH in vivo within a single injection. In addition, the C1-resonance allows...
Sequence analysis was performed with Unipro UGENE v1.16.1.13 An assay with dual-labelled probes (Eurofins) was designed as described by Van Poucke et al9 to genotype the KCNJ10 c.986T4C variant in additional animals. Experimental details on the genetic analysis are given in Supplementary ...
R. et al. Preoperative characterisation of clear-cell renal carcinoma using iodine-124-labelled antibody chimeric G250 (124I-cG250) and PET in patients with renal masses: a phase I trial. Lancet Oncol 8, 304–310 (2007). 38. Garousi, J. Comparative evaluation of antibody fragments- and ...
Eur J Nucl Med Mol Imaging 41(1):11–20 Afshar-Oromieh A, Avtzi E, Giesel FL, Holland-Letz T, Linhart HG, Eder M et al (2015) The diagnostic value of PET/CT imag- ing with the 68Ga-labelled PSMA ligand HBED-CC in the diagnosis of recurrent prostate cancer. Eur J Nucl ...
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Specifically, pyramidal neurons in the medial prefrontal cortex (mPFC) of GluN2C knockout mice have reduced mEPSC frequency and dendritic spine density and a contrasting higher frequency of mIPSCs. In addition a greater number of perisomatic GAD67 puncta was observed suggesting a potential increase...
I/R injury is also associated with neuroinflammation and pyroptosis, of which its mechanistic basis may be due to increased M1 microglia, which has been found post-injury in various organs, such as the brain [43,44], spine [45], heart [46], and retina [47]; these M1 microglia, in tu...
malachius. Our phylogeny did not support the close relationship of these two morphologically similar species and the grouping of collections labelled by both names within each phylogenetic species reflects unreliable species delimitations in the traditional literatures. Both species inhabit the wood of ...