series of C–H functionalization cascades and allows direct access to structurally diverse polycyclic heterocyles in one pot. The progress of these reaction cascades were fully con- trolled by oxidants and temperature. The proliferation of the reaction chain can be extended ...
C–H functionalization; cyclization; indazole products; transition metals catalysis Graphical Abstract 1. Introduction Nitrogen-based heterocyclic systems are commonly found in pharmaceutical agents and natural products, and they have been intensively explored as new bioactive products [1,2,3,4,5,6,7,...
visible-light-driven; α-C(sp3)–H bond; C–H bond functionalization; glycine derivatives Graphical Abstract 1. Introduction Visible light, a renewable energy resource, emerges as a prime reagent conducive to environmentally sustainable and green chemical synthesis. In recent decades, a noteworthy ...
Within a broad context, using H-bonds to position and orient substrates around active sites of proteins is recognized as playing a role in substrate functionalization [19]. Thus, our group sought to understand how H-bonds installed within the secondary coordination sphere might govern how a metal...