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About the Show With gun safety more and more on everyone's mind, some people are asking what Non-Lethal options there are. Byrna has the answer with the "un-gun"; utilizing Co2 and a variety of chemical and non-chemical projectiles, learn how Byrna can help protect anywhere, anytime....
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Luciferase mRNA was coinjected into the oocyte with 250 μM BLM (Table 4), and translation of the exogenous mRNA was decreased to 29% of control. Table 4. Inhibition of Protein Synthesis in Xenopus Oocytes by Onconase and BLM TreatmentResponse% Control Experiment A CPM Control, uninjected ...
Although >90% of uniquely mapped reads fell within known exons, the remaining data suggest new and revised gene models, including changed or additional promoters, exons and 3′ untranscribed regions, as well as new candidate microRNA precursors. RNA splice events, which are not readily measured ...
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of COVID-19 illness, has caused millions of infections worldwide. In SARS coronaviruses, the non-structural protein 16 (nsp16), in conjunction with nsp10, methylates the 5′-end of virally encoded mRNAs ...
Sequence analyses of small RNAs associating with the Drosophila Piwi proteins (Aubergine and Ago3) formed the basis for such a proposal, and these ideas are incorporated into the so-called ping-pong model (Brennecke et al., 2007, Gunawardane et al., 2007). It is proposed that antisense ...
MicroRNAs (miRNAs) are crucial molecules that regulate gene expression and hence pathways that are key to prostate cancer progression. These non-coding RNAs are highly deregulated in prostate cancer thus facilitating progression of the disease. Among the
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Using shotgun proteomics and ChIP sequencing, we demonstrate that leukodystrophy-causative mutations, but not TCS mutations, in POLR1C impair assembly and nuclear import of POLR3, but not POLR1, leading to decreased binding to POLR3 target genes. This study is the first to show that distinct ...