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Apoptosis induced by PGC-1 in breast cancer cells is mediated by the mTOR pathway. Oncol Rep 2013a;30: 1631-2163.Apoptosis induced by PGC-1β in breast cancer cells is mediated by themTOR pathway[J] . Libin Wang,Qilun Liu,Fang Li,Jing Qiu,Heng Fan,Haibin Ma,Yongzhao Zhu,Ligang ...
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In particular, we demonstrate that the levels of PGC-1 beta and mTOR correlated with overall mitochondrial activity. These results provide new evidence that cell apoptosis is orchestrated by the balance between several signaling pathways, and that PGC-1 beta takes part in these events in breast ...
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Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha Fasting-induced hepatic production of DHEA is regulated by PGC-1α, ERRα, HNF4α. Mol. Endocrinol. 23, 1171-1182.Grasfeder LL, Gaillard S, Hammes SR, Ilkayeva O, Newgard CB, Hochberg RB,...
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Paracrine cross-talk between skeletal muscle and macrophages in exercise by PGC-1α-controlled BNP. Sci. Rep. 2017, 7, 40789. [CrossRef] [PubMed]Furrer R, Eisele PS, Schmidt A, Beer M, & Handschin C (2017) Paracrine cross-talk between skeletal muscle and macrophages in exercise by PGC...
As PGC1β stability was decreased in vitro in sorafenib resistance in a proteasome-mediated process, this process is likely regulated by ubiquitin-mediated proteolysis as with most cellular proteins. We found that PGC1β expression was significantly decreased in sorafenib-resistant tumors in vivo (Fig...