DTI)、功能磁共振(functional magnetic resonance imaging,fMRI)、磁共振波谱分析(magnetic resonance spectroscopy,MRS)、正电子发射计算机断层扫描(positron emission tomography,PET)以及一体化PET/MRI脑功能检查等在bvFTD临床前期的研究中逐步展现出其各自不同的价值。
MRI是进行FTLD诊断和鉴别诊断的常规基础检查,推荐MRI用于疾病诊断、病情随访和判断预后(Ⅰ级推荐,A级证据)。 推荐11: 多模式脑影像通过综合分析皮质萎缩、白质完整性丧失、脑功能以及脑代谢改变来提供非常早期的客观证据,辅助临床对疾病做出早期的诊断及进展预测,但不作为FTLD常规诊断检查。推荐选用PET检查以提高诊断的准...
道德判断受损:出现行为举止不当、社交规则破坏等。• 创造力和抽象思维受损:包括语言难以理解、失去创造性 思维等。• 饮食行为改变:如过食、偏食、食量明显减少等。神经心理学评估:患者通常需要接受神经心理学评估,以评估认知功能和行为的变异。神经影像学:通常进行脑部神经影像学检查,如MRI 或PET扫描,以...
The bvFTD phenocopy syndrome: a case study supported by repeated MRI, [18F]FDG-PET and pathological assessmentBehavioral variant frontotemporal dementiamisdiagnosisneuropsychiatryphenocopy syndromediagnostic distinction of bvFTD and primary psychiatric diseases...
The behavioral variant of frontotemporal dementia (bvFTD) presents with variable patterns of cortical and subcortical atrophy on Magnetic Resonance Imaging (MRI). We aimed to assess the clinical utility of two reproducible measurements of cerebral atrophy (Harper's visual atrophy scale [HVAS], and ...
P1‐331: GROUP RELATED MRI DIFFERENCES BETWEEN BVFTD PATIENTS AND COGNITIVELY NORMAL CONTROLSdoi:10.1016/j.jalz.2019.06.886AnaMontrealLauraMontrealManeraMontrealMahsaMontrealDadarMontrealSimonMontrealDucharmeMontrealLouisMontrealCollinsMontrealAlzheimer's & Dementia...
Patients underwent structural MRI; we used voxel-based morphometry to examine relationships between regional atrophy and ToM impairment and caregiver burden.FP task performance was impaired in bv-FTDp and negatively associated with caregiver burden. Atrophy was found in areas involved in ToM. Caregiver ...
Mapping brain morphological and functional conversion patterns in amnestic MCI: a voxel- based MRI and FDG-PET study. European Journal of Nuclear Medicine and Molecular Imaging, 37(1):36-45, 2010.
Cardiovascular autonomic function in frontotemporal dementia, behavioral variant (FTDbv)Longitudinal clinical, neuropsychological, MRI studydoi:10.1016/j.jns.2013.07.1227Struhal, W.Ransmayr, G.ESJournal of the Neurological Sciences