Together, these data suggest that the burst-firing patterns of pyramidal cells may be a neural biomarker of depressive-like mice and antidepressant action. Furthermore, synaptic transmission and BDNF may contribute to the rapid antidepressant-like effects on depression. 展开 ...
2007. Cellular mechanisms of burst firing-mediated long-term depression in rat neocortical pyramidal cells. J. Physiol. 578:471-79Czarnecki, A., Birtoli, B. & Ulrich, D. (2007) Cellular mechanism of burst firing mediated long-term depression in rat neocortical pyramidal cells. J. Physiol.,...
Activity-deprivation by 48 h TTX treatment increases the spontaneous firing rate of cultured hippocampal neurons while regularizing their bursting. Spontaneous membrane potential fluctuations and firing of hippocampal neurons are shown in (A) (control) and (B) (after 48 h of TTX-treatment). (C) M...
Decoding Depression: Insights from Glial and Ketamine Regulation of Neuronal Burst Firing in Lateral Habenuladoi:10.1101/SQB.2018.83.036871Yihui CuiYan YangYiyan DongHailan HuCold Spring Harb Symp Quant Biol