Bupropion hydrochloride 是去甲肾上腺素和多巴胺神经递质的双重高效抑制剂,IC50 值分别为 6.5 ± 0.6 μM 和 3.4 ± 0.4 μM [1]. Bupropion hydrochloride 是一种氨基酮,作为非尼古丁以帮助戒烟.Bupropion hydrochloride 也 是经典的抗抑郁药,能够干扰去甲肾上腺素\血清素和多巴胺的摄取[2].此外,Bupropion ...
Bupropion hydrochloride is currently available in three formulations: immediate-release, sustained-release, and extended-release (ER). Several published reports exist concerning bupropion's history of inducing seizures in both the immediate- and sustained-release formulations. Although the potential of the...
MCE 站:Threo-dihydrobupropion hydrochloride 产品活性:Threo-dihydrobupropion hydrochloride 是安非他酮的初级代谢产物,可用于抑郁、行为学和生物化学研究。 研究领域:Metabolic Enzyme/Protease 作用靶点:Drug Metabolite 相关产品:Clozapine N-oxide | Oseltamivir acid | Urolithin A | GS-443902 trisodium | Mycophenola...
Bupropion hydrochloride 3D printing Liquid crystal display (LCD) Braille imprint Personalized medicine Sustained release 1. Introduction Personalized medicine has been proposed as a remedy to ensure the safe, efficient utilization and minimization of the side effects of medications with narrow therapeutic in...
Prescribing Information: Wellbutrin XLt (Bupropion Hydrochloride Extended-Release Tablets). Glaxo- SmithKline: Research Triangle Park, NC. Grabowski J, Rhoades H, Stotts A, Cowan K, Kopecky C, Dougherty A et al (2004). Agonist-like or antagonist-like treatment for cocaine dependence with ...
preparationofbupmpionhydrochloridesustainedreleasetablets.DiferentHPMCviscosity,Consumption,particlesize,compression pressureandslurryrotationalspeedandotherfactors,analysistheinfluenceondrugreleaserate.Throughthereleaseoftestevaluationof sustainedreleaseefect,andthepreliminarystudyonthedrugreleasecharacteristic.Withhydroxypropyl...
Chapter Bupropion Hydrochloride Profiles of Drug Substances, Excipients and Related Methodology Book series2016,Profiles of Drug Substances, Excipients and Related Methodology S.R.Khan, ...P.J.Faustino Explore book 6.2.3Metabolism Bupropionis extensively metabolized in humans byhepatic enzymes(primarily CY...
Prescribing Information: Belviq (lorcaserin hydrochloride) tablets. In: Eisai Inc., 2013. Prescribing Information: Qsymia (phentermine and topiramate extended-release) capsule. In: Vivus, Inc., 2014. Prescribing Information: Contrave (naltrexone HCl and bupropion HCl) Extended-release Tablets. In: Take...
Switching from hydrochloride salt formulation to hydrobromide salt (Aplenzin): 150 mg/day hydrochloride salt = 174 mg/day hydrobromide salt; 300 mg/day hydrochloride salt = 348 mg/day hydrobromide salt; 450 mg/day hydrochloride salt = 522 mg/day hydrobromide salt ...
German Patent DE69937650 Kind Code: D1 Abstract: The invention provides a controlled release tablet, free of stabilizer and free of pore-forming agent comprising: (i) a core consisting essentially of bupropion hydrochloride, a binder and a lubricant; and (ii) a coating consisting essentially of...