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The long axis of the N protein is approximately perpendicular to the helix axis, with its RNA-binding cleft oriented towards the tip of the virion. The 3′ end of the genomic RNA is therefore at the domed end of the particle and the 5′ end, at the blunt end of the particle. To ...
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Nevertheless, we should recognize that the colibactin footprint in CRC genomes and corresponding driver genes may represent only the tip of the iceberg of the impact of pks+ E. coli [52]. A recent study has demonstrated that infection with pks+ E. coli fails to induce a typical colib...