基本信息 文章标题:Integrative analysis of single‑cell and bulk RNA‑sequencing data revealed T cell marker genes based molecular sub‑types and a prognostic signature in lung adenocarcinoma发表时间:2024-01-10 发表杂志:Scientific Reports 影响因子:4.997 在线阅读链接: https://www.nature.com/articl...
由于AD组NK细聚类显著减少(Figure 2B, F),进行了NK cluster DEGs的GO analysis and分析(Figure 3C, D),发现主要富集于抗原加工和免疫反应有关通路。 Figure 3 IRG scores of PBMC cell clusters in AD. 3、对AD患者大脑的BulK-seq数据进行差异基因分析---DEGs of AD Brain From Bulk Sequencing Data BulK-...
SUMMARY Bulk segregation analysis (BSA) utilizes a strategy of pooling individuals with extreme phenotypes to conduct economical and rapidly linked marker screening or quantitative trait locus (QTL) mapping. With the development of next‐generation sequencing (NGS) technology in the past 10 years, BSA...
早!今天小编和大家分享一篇22年11月发表在Frontiers in Immunology(IF:8.786)杂志的文章《Identification and validation of a signature based on macrophage cell marker genes to predict recurrent miscarriage by integrated analysis of sin...
题目:Integrative Analysis of Bulk and Single-Cell RNA Sequencing Data Reveals Cell Types Involved in Heart Failure期刊:Front Bioeng Biotechnol.(Q1 IF:5.7) 日期:05/January/2022 DOI:https://doi.org/10.3389/fbioe.2021.779225 心力衰竭(HF)是一种慢性进行性综合症,死亡率很高。HF是一种严重的心功能障...
今天小编和大家分享一篇22年11月发表在Frontiers in Immunology(IF:8.786)杂志的文章《Identification and validation of a signature based on macrophage cell marker genes to predict recurrent miscarriage by integrated analysis of single-cell and bulk RNA-sequencing》。作者通过单细胞和bulk RNA测序的联合分析,...
Figure 6 scRNA analysis of NK cells in AD brain. 小结 此文章的单细胞(ScRNA)测序联合Bulk-seq分析的生信成文思路,非常经典。不难看出,此文借用了肿瘤生信分析的思路,而本文研究的疾病是非肿瘤类疾病。此外,若想拓展更多的非肿瘤类疾病的生信发文思路,也可借用肿瘤的相关思路(如更换热点基因数据集或你感兴趣的...
今天给大家介绍的 就是这篇发表在《Frontiers in Genetics》上题为"Integrated analysis of bulk and single-cell RNA sequencing reveals the interaction of PKP1 and tumor-infiltrating B cells and their therapeutic potential for nasopharyngeal carcinoma" 的文章,IF= 4.8 。作者在文章的Acknowledgement也是对我们...
5、功能分析(GO Analysis) 采用NCBI/UNIPROT/SWISSPROT/AMIGO等GO数据库,对于差异基因进行功能分析,从而得到差异基因所显著性富集的功能条目(GO Term)。 6、信号通路分析(Pathway Analysis) 整合KEGG、NCBI、EMBL等数据库,深入优化所需算法,对差异基因进行信号通路分析,得到差异基因所显著性富集的信号通路条目。
今天小编和大家分享一篇22年11月发表在Frontiers in Immunology(IF:8.786)杂志的文章《Identification and validation of a signature based on macrophage cell marker genes to predict recurrent miscarriage by integrated analysis of single-cell and bulk RNA-sequencing》。作者通过单细胞和bulk RNA测序的联合分析,...