Evaluation of Buccal PatchesBuccal route is an attractive route of administration for systemic drug delivery and it leads direct access to the systemic circulation through the internal jugular vein bypasses drugs from the hepatic first pass metabolism provides high bioavailability. Buccalbioadhesive films,...
Related to buccal:buccal tablet,buccal administration buc·cal (bŭk′əl) adj. Of or relating to the cheeks or the mouth cavity. [From Latinbucca,cheek.] buc′cal·lyadv. American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcou...
Within the oral mucosal cavity, the buccal region offers an adorable route of administration for systemic drug delivery. Among the various transmucosal sites available, mucosa of the buccal cavity was found to be the most convenient and easily approachable site for the delivery of therapeutic agents...
8.7 Other routes of administration Electrosprayed particles for other ROAs such as buccal, topical and brain offer a number of possibilities [200,201]. Buccal mucosa is a promising route for systemic drug delivery, owing to its convenience, accessibility and high vasculature. ES has been used to...
The buccal region offers an attractive route of administration for systemic drug delivery. Glimepiride is a potent drug against Diabetes mellitus-II with a half life of 3-5 hours. Though Glimepride has 100% oral absorption, due to high first pass metabolism its bioavailability is less. The ...
The sublingual route tended to be associated with more side effects.JoyceChaiandChingYinGraceWongandPakChungEBSCO_AspContraceptionChai J, Wong CY, Ho PC. A randomized clinical trial comparing the short- term side effects of sublingual and buccal routes of misoprostol administration for medical ...
Administration of drugs via the buccal route has attracted much attention in recent years. However, developing systems with satisfactory adhesion under wet conditions and adequate drug bioavailability still remains a challenge. Here, we propose a mussel-inspired mucoadhesive film. Ex vivo models show th...
Children were randomly assigned to receive lorazepam, 0.1 mg/kg, by the buccal, intranasal or intravenous route. The primary endpoint was seizure cessation within 10 min of drug administration. Results There were 761 seizures analysed, with 252 patients in the buccal, 245 in the intranasal and ...
Secretion from submucosal salivary glands of the ferret in response to a cholinesterase inhibitor applied onto the oral mucosa. Parasympathomimetics or cholinesterase inhibitors taken orally may relieve dry-mouth symptoms, but this route of administration is often associated with ad... J Ekström,HF...
Within the oral mucosal cavity, the buccal region offers an adorable route of administration for systemic drug delivery. Among the various transmucosal sit... Patel,Anay,R.,... - 《International Journal of Pharmacy & Life Sciences》 被引量: 17发表: 2011年 BUCCOADHESIVE DRUG DELIVERY SYSTEMS: ...