Survival rates are good if plague is diagnosed and treatment is started promptly but because of the generalized nature of these symptoms a diagnosis is often delayed, and if this is the case, even with medical intervention, 50% of patients may die, probably as a result of the induction of ...
In vivo, the survival rate for mice treated with CIN+GEN was similar to that observed with CIN alone and slightly higher than that observed for GEN alone 100, 100 and 85%, respectively when treatment was started 44 h post challenge. 100% of survivors were recorded in the CIN+GEN group ...
but it is Septicemic and Pneumonic Plagues that were responsible for the large amount of deaths. The plague continued to be a menace in later centuries. The Great Plague of London in the 17th century killed one fifth of the population. The plague still exists today but it is highly treatabl...
“There is no single model of ‘the pandemic’ or a ‘plague outbreak’ that can be applied to any place at any time regardless of the context,” says Adam Izdebski, the leader of the Palaeo-Science and History group at the MPI SHH. “Pandemics are complex phen...
Bubonic plague caused by Yersinia pestis is highly infectious and often fatal. Characterization of the host immune response and its subsequent suppression by Y. pestis is critical to understanding the pathogenesis of Y. pestis. Here, we utilized single-cell RNA sequencing to systematically profile the...