Cats are highly susceptible to the plague and can catch it from flea bites or a rodent scratch or bite, or by ingesting a rodent. Cats may also die if not properly treated with antibiotics, officials said. Dogs are not as susceptible to plague, according to the statement. However, dogs c...
route(median lethal dose [LD50]: 1–2CFU73) is considered to mimicbubonic plague, whereas the exposure of mice to the bacteria via inhaled aerosols results in the pneumonic form of the disease (LD50: 2 × 104CFU74). The efficacy of the original Cutter Killed Whole Cell (KWC) vaccine ...
plague in Italy killed two-thirds of the population of Naples and Genoa, and London lost roughly a quarter of its population. An outbreak in Moscow in 1770 killed about 100,000 people.
The plague bacteria are killed within polymorphonuclear leukocytes, but persist within monocytes and express various virulence determinants, thereby allowing growth and eventual release from the monocytes.49 One such virulence determinant is the pH6 antigen, a fibrillar adhesin induced by the low phagosoma...