方法采用减低剂量的Bu/Cy+ATG方案,进行异基因造血干细胞移植治疗18例恶性血液病,预处理方案是:马利兰(BU)4 mg/(kg·d)×3,环磷酰胺(CY)60mg/(kg·d)×2,司莫司汀(Me-CCNU)450mg/(m2·d)×1,抗胸腺细胞球蛋白(ATG)3mg/(kg·d)×2。采用环孢素A+霉酚酸酯(MMF)+短程MTX预防GVHD。结果18例患者...
ATG 2 例 ,使用费城尤斯 34 例 ,使用 ALG 1例。 五、对症支持治疗及并发症的预防 所有患者移植前人住无菌层 流病房 ,预处理过 程 中水化 和碱化尿液 预防出血性膀胱炎 。静脉注 射肝素钠预 防肝静脉闭塞综合征 ,一9- +35 d应用肝 素钠80 Iu ·kg～·d一。预防感染包括 :静脉注射头孢 ...
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In multivariate analysis, age, cytogenetic risk groups, use of ATG and interval from diagnosis to alloSCT were not significant prognostic factors for survival. In all, these results suggest that in AML patients in Rel 1 undergoing myeloablative alloSCT, Bu/Cy and TBI/Cy conditioning regimens can...
采用减低剂量的Bu/Cy+ATG方案,进行异基因造血干细胞移植治疗18例恶性 血液病,预处理方案是:马利兰(BU) 4mg/(kg?d)×3,环磷酰胺(CY)60mg/(kg?d)×2,司莫司汀 (Me—CCNU)450mg/(m?d)×1,抗胸腺细胞球蛋白 (ATG)3mg/(kg?d)×2.采用环孢素A+霉酚酸酯(MMF)+短程MTX预防GVHD.结 ...
Fig:1 Conclusion: In conclusion, the study suggests that the Flu/Bu/Cy/ATG conditioning regimen resulted in better overall survival [OS] and thalassemia GVHD free survival [TGFS] compared to Flu/Thio/Treo regimen in a high-risk transfusion dependent thalassemia [TDT] patients undergoing allo-...
GVHD prophylaxis was PTCy卤CNI卤m-TOR inhibitor in 32 (45%) or ATG卤CNI in 39 (55%) patients. The primary end points were TRM, relapse-free survival (RFS), graft-versus-host disease (GVHD) free, relapse free survival (GRFS) and overall survival (OS). Secondary end points included ...
Outcomes After Addition Of Rabbit-ATG To The Standard BU + CY Preparative Regimen For Allogeneic Matched Sibling Donor (MSD) Hematopoietic Stem Cell Transplantation (HSCT) For Hemoglobinopathies In Childrendoi:10.1016/j.bbmt.2009.12.265.