Calorie restriction (CR) and exercise training (EX) are two critical lifestyle interventions for the prevention and treatment of metabolic diseases, such as obesity and diabetes. Brown adipose tissue (BAT) and skeletal muscle are two important organs for
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body fat in DJ-1 KO mice was mainly due to a reduction in the mass of epididymal white adipose tissue (eWAT), subcutaneous white adipose tissue (sWAT) and brown adipose tissue (BAT), but not other tissues, without lower free fatty acid (FFA) in plasma (Supplementary Figure S1A–D). ...
4171Accesses 40Citations Metrics Abstract DJ-1 protein is involved in multiple physiological processes, including Parkinson’s disease. However, the role of DJ-1 in the metabolism is largely unknown. Here we found that DJ-1 maintained energy balance and glucose homeostasis via regulating brown adipo...
International Journal of Molecular Sciences Article Adaptive Thermogenesis in a Mouse Model Lacking Selenoprotein Biosynthesis in Brown Adipocytes Lucia A. Seale 1,2,* , Ashley N. Ogawa-Wong 1, Ligia M. Watanabe 1,†, Vedbar S. Khadka 3 , Mark Menor 3, Daniel J. Torres 1,2 , Bradley ...
Langdon picked up the receiver. “Hello?” “Monsieur Langdon?” a man’s voice said. “I hope I have not awoken you?” Dazed, Langdon looked at the bedside clock. It was 12:32 A . M . He had been asleep only an hour, but he felt like the dead. “This is the concierge...