The enzymatic conversion of allyl alcohol to 2,3-bromochloro-, bromoiodo-, and fluoroiodo-l-propanols by various haloperoxidases is reported. This represents the first enzymatic transformation of an unhalogenated organic substrate to heterogeneous dihalide derivatives. Synthesis of the fluoroiodo-...
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol regioselective reaction; With potassium carbonate In isopropyl alcohol at 80℃; for 24h; 36082-50-5 2,4-dichloro-5-bromopyrimidine 68621-88-5 (3-aminophenyl)carbamic acid tert-butyl ester 1202760-30-2 tert-butyl (3-((5-bromo...
This dimer was immediately oxidized by FMO3 or atmospheric oxygen to the final product, M4. No evidence was found for the P450-mediated production of an aliphatic alcohol from indoline that might dehydrate to produce indole. Therefore, P450 enzymes catalyze the novel "aromatase" metabolism of ...
Soluble in ace- tone, alcohol, benzene, and ether; slightly soluble in water. Bromoacetone appears as a clear colorless liquid turning violet on standing, even in the absence of air, and decomposing to a black resinous mass on long standing. Denser than water and poorly soluble in water....
Amphidinolide E was hydrogenated (H2, Rh/Al2O3), further reduced (LiAlH4), and the resultant alcohol (65) converted to bis-isopropylidene 66 (Scheme 10). Sign in to download full-size image Scheme 10. Chemical conversion of amphidinolide E (63). The AC of amphidinolide E (63...
The conversion of N-enyl substituted formyl pyrazole 87 by reduction of aldehyde to alcohol followed by reaction with vinyl/allylmagnesium bromide in THF provides dienylpyrazoles 88 needed for RCM reaction. The 5 mol% of Ru-III catalyst (Hoveyda-Grubbs’) in dichloromethane under reflux conditions...
Time-conversion plots of the lactonization of 2a in methanol at 60°C in the dark. The thermal stability of 2a in some solvents was examined in the dark. The conversion of 2a into 7a took place in an alkyl alcohol such as methyl, ethyl, 1-propyl, 2-propyl, or t-butyl alcohol at ...
Herein, a method for synthesizing various alkyl trifluoromethyl and alkyl bromodifluoromethyl ethers using carbonofluoridothioates (R–OC(=S)F) as precursors has been described. Carbonofluoridothioates were obtained upon the reaction of an alcohol and S=CF2generatedviathe decomposition of an SCF3...
One-Pot Approach to the Conversion of Alcohols into α-Iodo-α,β-unsaturated Esters (Carboethoxymethylene)triphenylphosphorane 1 can undergo the tandem reaction of iodination–oxidation–Wittig reaction with alcohol in the presence of N-io... Usama Karama - 《Cheminform》 被引量: 28发表: 2010年...
Then, the reaction with p-TsOH in refluxing C6H6, while eliminating H2O, removed the alcohol to provide the indene. The reaction with O3 followed by Me2S and aqueous NH3 provided 5,8-dimethyl-7-nitroisoquinoline easily. The nitroisoquinoline reduced unexpectedly rapidly with NH2NH2 and Raney-...