Safety and preliminary efficacy of nabiximols oromucosal cannabinoid spray plus dose-intense temozolomide (DIT) was evaluated in patients with first recurrence of GBM. Methods Part 1 was open-label and Part 2 was randomised, double-blind, and placebo-controlled. Both required individualised dose ...
The natural history and treatment landscape of primary brain tumours are complicated by the varied tumour behaviour of primary or secondary gliomas (high-grade transformation of low-grade lesions), as well as the dilemmas with identification of radiation necrosis, tumour progression, and pseudoprogression...
Psychiatric co-morbidity has also been described and most cases are due to mutations in the epsilonsarcoglycan gene (SGCE).BMJJournal of Neurology Neurosurgery & Psychiatry
- 《Journal of Neurology Neurosurgery & Psychiatry》 被引量: 187发表: 2009年 Linking Research and Marketing Opportunities for Pulses in the 21st Century The cool season food legumes are important in the nutrition of populations and livestock in many countries and play a valuable role in ...
Department of Neurosurgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX 77030-4009, USA Shaan M Raza & Franco DeMonte Corresponding author Correspondence toEhab Y Hanna. Ethics declarations Competing interests ...
In patients with human epidermal growth factor receptor-2 (HER2)-overexpressing breast cancer, treatment with trastuzumab has been shown to markedly improve the outcome. We investigated the role of trastuzumab on brain metastasis (BM) in HER2-positive br
As the license of dopamine agonists extends to other conditions such as restless leg syndrome (RLS) we audited our clinical practice of the advice given to patients.JDepartmentADepartmentJohnstonDepartmentMDepartmentHillDepartmentBMJJournal of Neurology Neurosurgery & Psychiatry...
Department of Neurosurgery, The Johns Hopkins Hospital – The John Hopkins University School of Medicine, 1800 Orleans Street, Baltimore, MD, 21287, USA Daniel M. Sciubba Department of Medicine, Division of Hematology/Oncology, Massachusetts General Hospital – Harvard Medical School, 55 Fruit Street...
Glioblastoma multiforme (GBM) is the most common primary brain tumour in adults and continues to portend poor survival, despite multimodal treatment using surgery and chemoradiotherapy. The addition of tumour-treating fields (TTFields)—an approach in wh
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