4. 作者:Frederick Bradbury:[Bradbury's Book of Hallmarks] : A Guide to Marks of Origin on English, Scottish and Irish Silver, Gold and Platinum and on Foreign Imported Silver and Gold Plate 1544 to 2010 弗雷德里克·布拉德伯里(Frederick Bradbury) 布拉德伯里的标志系统:原产地在英格兰,苏格兰和爱尔...
Besides the classical six hallmarks of cancer proposed by Hanahan et al., avoiding immune destruction has emerged as a new hallmark of cancer.1Complex interactions between cancer and immune system exist, which are controlled by multiple mechanisms. Among these mechanisms, cancer cells can avoid immun...
The Hallmarks of cancer. Cell. 2000;100:57–70. Article CAS PubMed Google Scholar Antal T, Krapivsky PL, Nowak MA. Spatial evolution of tumors with successive driver mutations. Phys Rev E. 2015;92:022705. Article Google Scholar Lewis D, Roncaroli F, Agushi E, Mosses D, Williams R...
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144 (5): 646–674. Article CAS Google Scholar Hanna N, Shepherd FA, Fossella FV, Pereira JR, De Marinis F, von Pawel J, Gatzemeier U, Tsao TC, Pless M, Muller T, Lim HL, Desch C, Szondy K, Gerv...
In vitro model systems are important tools in cancer research to identify carcinogens, their involvement in molecular pathways during tumour growth and metastasis, and drug testing and development [54,55]. In his third hallmarks of cancer paper, Hanahan proposed fourteen biological properties leading ...
Although CPI therapies benefit only a minority of patients, this is still a considerable minority. Moreover, CPIs have become gold-standard first-line treatments with curative potential for many cancer types, even in the metastatic setting [13, 147,148,149,150]. Thus, the clinical landscapes...
Gastrointestinal (GI) cancers account for 35% of cancer-related deaths, predominantly due to their ability to spread and generate drug-tolerant metastases. Arising from different locations in the GI system, the majority of metastatic GI malignancies colo
4. 作者:Frederick Bradbury:[Bradbury's Book of Hallmarks] : A Guide to Marks of Origin on English, Scottish and Irish Silver, Gold and Platinum and on Foreign Imported Silver and Gold Plate 1544 to 2010 弗雷德里克·布拉德伯里(Frederick Bradbury) ...