Why do Brits say sod it? If someone calls another person or something such as a job a sod, theyare expressing anger or annoyance towards that person or thing. If someone uses an expression such as sod it, sod you, or sod that, they are expressing anger or showing that they do not ca...
Bollocking –a strong reprimand, a telling-off. Bollocks! –an expression of dismissive contempt or disagreement, same as “Rubbish!” Bonkers –crazy Boot– rear compartment of the car, used for storage (American: trunk) Bop –(v) to dance or (n) a dance; a term often used by univers...
Throw a spanner in the works - This is an expression that means to wreck something. wangle accomplishing something by scheming or trickery Most people that wangle stuff are usually quite good at haggling. sod surface layer of ground containing a mat of grass and roots Sod - This word has...
Spoiler alert: Brummie is spoken by Tom Shady in Peaky Blinders.Aside from the accent, regional variations of British English also include different slang words used in different regions of the UK. Here are some of the
Additionally, a slight increase in RyR2 protein expression was also observed in this group (Figure S4b). In the first phase of our study, we examined the potential of MP-010 to ameliorate motor impairments and neuromuscular dysfunction in SOD1G93A transgenic mice. To this end, the animals ...
Clear off!- This expression brings back memories of being a kid and stealing apples from people's gardens. Sometimes we would get caught and some old bloke would come out and shout "oi clear off you lot". It basically means get lost. ...
The data show that expression of SOD2 and CAT in PC cells is increased within 8 h of gemcitabine treatment and continues to increase with time (Supplementary Figure 6). It is; however, likely that SOD2 and CAT upregulation in Gem-Exo-treated PC cells may occur through other, not yet...
In contrast, tumour-associated mutant p53 proteins (R175H or R280K) caused enhanced Nox4 expression and cell migration in both TGF-β-dependent and TGF-β-independent pathways. Moreover, knockdown of endogenous mutant p53 (R280K) in TGF-β-treated MDA-MB-231 metastatic breast epithelial cells...
malignant cells are dependent on its enzymatic activity to sustain pyrimidine synthesis.100In fact, inhibition of DHODH through specific antagonists decreases cell growth in many cancer cell lines, in particular acute myeloid leukaemia, and high expression of DHODH correlates with higher-grade gliomas,98...
alternative methods that integrate multiple data sources such as gene expression, protein–protein interactions or pathway analyses may be used to aggregate the effect of multiple variants with small effects.72Such approaches could increase the power of the analyses while better explaining the underlying...