Peng Y, Chen L, Li S, Zhang Y, Xu R, Liu Z, Liu W, Kong J, Huang X, Wang Y, et al (2018) BRI1 and BAK1 interact with G proteins and reg- ulate sugar-responsive growth and development in Arabidopsis. Nat Commun 9
BAK1, as a co-receptor of BRI1 (AT4G39400) that mediates brassinosteroids (BR) signaling, the functional roles of BAK1, as a versatile co-receptor for various ligand-binding leucine-rich repeat (LRR)-containing receptor-like kinase (RLKs), are being extended to involvement with plant immunit...
The activation of BRASSINOSTEROID INSENSITIVE1 (BRI1) and its association with the BRI1 ASSOCIATED RECEPTOR KINASE1 (BAK1) are key steps for the initiation of the BR signaling cascade mediating hypocotyl elongation. Heat shock protein 90 (HSP90) is crucial in the regulation of signaling processe...
Furthermore, BRI1 and BAK1 interact in vitro and in vivo. In addition, it was determined that BRI1 and BAK1 can phosphorylate one another, and the autophosphorylation activity of BAK1 is stimulated by BRI1. Expression of an inactive protein kinase BAK1 mutant also produced a strong bri1 ...
Together, these findings suggest that plant steroid-hormone signaling is dispensable for the containment of infection-induced PCD. We propose a novel, BL-independent function of BAK1 in plant cell-death control that is distinct from its BL-dependent role in plant development....
Anti-BAK1 | Brassinosteroid insensitive 1-associated receptor kinase 1 AS12 1858| Clonality:Polyclonal| Host:Rabbit| Reactivity:Arabidopsis thaliana, Solanum lycopersicum AS16 3204| Clonality:Polyclonal| Host:Rabbit| Reactivity:A. thaliana, N. benthamiana...
The plasma membrane proteins BRI1-associated receptor kinase 1 (BAK1)8, 9, BR-signaling kinase 1 (BSK1)10, and BRI1 kinase inhibitor 1 (BKI1)11 are involved in BR signaling by associating with BRI1. BRI1 is localized not only to plasma membranes but also to endosomes12. The ...
BRI1 transphosphorylates BAK1 in vitro on specific kinase-domain residues critical for BAK1 function. BAK1 also transphosphorylates BRI1, thereby quantitatively increasing BRI1 kinase activity toward a specific substrate. We propose a sequential transphosphorylation model in which BRI1 controls signaling...
BRI1和BAK1与G蛋白发生物理相互作用,而G蛋白是介导糖信号传导必不可少的。生化数据表明,BRI1可以磷酸化G蛋白的β亚基和γ亚基,而BAK1可以磷酸化G蛋白的γ亚基。遗传分析表明,BRI1和BAK1在与G蛋白亚基共同调节糖应答的途径中起作用。因此,我们的发现揭示了BR受体与G蛋白缔合以调节糖响应性生长和发育的重要遗传和...
Two of the well-studied LRR-RLKs are brassinosteroid-insensitive 1 (BRI1), the brassinosteroid (BR) receptor, and BRI1-associated kinase 1 (BAK1) that serves as a coreceptor for BRI1 activation [3-5]. BRs are plant-specific steroids that play essential roles in a wide range of ...