The attending obstetrician expressed concern to us about the LC counseling patients and invoking “personal experience” in the absence of published data as evidence for progesterone-related reduction in milk supply. She expressed concerns that sharing information about a theoretical risk was inappropriate...
ADCs are being developed under the premise of producing increased cytotoxicity with a concomitant reduction in chemotherapy off-target AEs. ADCs are molecules composed of an antibody linked to a chemotherapy payload. These linkers can be classified into two main groups, cleavable and noncleavable, on...