(2) the procedure’s degree of risk reduction and impact on survival; (3) surgical techniques, potential surgical complications and long-term sequelae; and (4) alternatives to surgery. Surgeons should encourage shared and informed decision making with patients who have an elevated lifetime risk ...
ADCs are being developed under the premise of producing increased cytotoxicity with a concomitant reduction in chemotherapy off-target AEs. ADCs are molecules composed of an antibody linked to a chemotherapy payload. These linkers can be classified into two main groups, cleavable and noncleavable, on...
In addition, despite the extensive screening utilizing MRI, some early-stage breast cancers were missed, highlighting the recommendations to undergo risk reduction mastectomy for women with high-risk PVs. Author Contributions Conceptualization: X.W. and B.L.N.; methodology: X.W.; data analysis: ...
A large-scale study of the ultrawideband microwave dielectric properties of normal breast tissue obtained from reduction surgeries. Phys. Med. Biol. 2007, 52, 2637–2656. [Google Scholar] [CrossRef] [Green Version] Lazebnik, M.; Popovic, D.; McCartney, L.; Watkins, C.B.; Lindstrom, M...
The results of the present work support the hypothesis that greater adherence to Mediterranean-type dietary pattern may lead to a reduction in breast cancer risk through modulation of the CRP concentration. Moreover, evidence has accumulated that adhering to a Mediterranean-type diet facilitates weight...
Although overdiagnosis estimates are associated with a high degree of uncertainty, estimates of magnitude for the two outcomes of screening—the reduction in breast cancer mortality and overdiagnosis—differ across studies. Though the balance between the advantages and disadvantages of breast cancer screenin...